| Brand Name | Solu-Cortef |
| Generic Name | Hydrocortisone |
| Drug Class | Systemic Corticosteroid |
| Availability | Prescription |
| Manufacturer | Pfizer |
| Indications | Induction of remission in severe IBD (hospitalized patients) |
| Type | Tablet, Cream, Injection |
| Doses | 100 mg IV every 6–8 hrs, then taper |
| Route | IV |
| Side Effects | Skin thinning (topical), GI upset, increased infection risk (oral) |
| Interactions | Can alter immune response; interacts with anticoagulants |
| Overdose | Electrolyte imbalance, adrenal suppression. |
| Missed Dose | Take ASAP; tapering required. |
| Contraindications | Fungal infections, untreated systemic infections. |
| Alternatives | Prednisone, Budesonide |
| Co-Pay Assistance Program | Available OTC |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Hydrocortisone is a corticosteroid that is employed in inflammation, allergic response, eczema and rheumatoid arthritis.
Hydrocortisone functions by suppressing inflammation and suppressing the response of the immune system.
The main side effects are that it increases weight, blood sugar and mood.
No, Hydrocortisone must be used with food in order to decrease the chances of stomach irritation.
Hydrocortisone can only be used during pregnancy when the advantages will surpass the dangers. It should only be used in consultation with your physician.
In case you forgot to take a dose you should do so as soon as you can notice unless it is nearly near your next dose. Do not take two doses at once.
Hydrocortisone normally begins its action in a several hours to decrease inflammation to alleviate symptoms.
When using Hydrocortisone on long-term basis, a healthcare provider should keep track of its side effects like bone loss and hypertension, among others.
In case of such serious side effects as a significant weight increase, excessive mood swings, or shortness of breath, call your doctor.
Yes, Hydrocortisone may react with such drugs as blood thinners, diuretics, and some drugs used to treat diabetes. You should notify your physician of any medications that you are taking.
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