| Brand Name | Solu-Cortef |
| Generic Name | Hydrocortisone |
| Drug Class | Systemic Corticosteroid |
| Availability | Prescription |
| Manufacturer | Pfizer |
| Indications | Induction of remission in severe IBD (hospitalized patients) |
| Type | Tablet, Cream, Injection |
| Doses | 100 mg IV every 6–8 hrs, then taper |
| Route | IV |
| Side Effects | Skin thinning (topical), GI upset, increased infection risk (oral) |
| Interactions | Can alter immune response; interacts with anticoagulants |
| Overdose | Electrolyte imbalance, adrenal suppression. |
| Missed Dose | Take ASAP; tapering required. |
| Contraindications | Fungal infections, untreated systemic infections. |
| Alternatives | Prednisone, Budesonide |
| Co-Pay Assistance Program | Available OTC |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Hydrocortisone is a corticosteroid used to treat inflammation, allergic reactions, and conditions like eczema and rheumatoid arthritis.
Hydrocortisone works by reducing inflammation and modulating the immune system's response.
Common side effects include weight gain, increased blood sugar, and mood changes.
Yes, Hydrocortisone should be taken with food to reduce the risk of stomach irritation.
Hydrocortisone should only be used during pregnancy if the benefits outweigh the risks. Consult your doctor before use.
If you miss a dose, take it as soon as you remember unless it's close to your next dose. Do not take two doses at once.
Hydrocortisone typically starts to work within a few hours to reduce inflammation and relieve symptoms.
Long-term use of Hydrocortisone requires monitoring by a healthcare provider to manage potential side effects, such as bone loss and high blood pressure.
If you experience severe side effects like rapid weight gain, severe mood changes, or difficulty breathing, contact your doctor immediately.
Yes, Hydrocortisone can interact with medications like blood thinners, diuretics, and certain diabetes medications. Inform your doctor about all medications you're taking.
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