Brookshire Cypress Jersey Village Katy
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Plenvu Bowel Preparation (Afternoon)

Dr. Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG

Follow our expert guide on using Plenvu for a complete colon cleanse before an afternoon colonoscopy. Get step-by-step instructions today!

Schedule Appointment 832-632-4070

Video Instructions

Written Instructions

General Instructions

2 Weeks Before the Procedure
Foods No change
Liquids Drink plenty of water

1 Week Before the Procedure
Foods

No Nuts or Seeds - berries, cashews, corn nuts, peanuts, pecans, popcorn, walnuts

Low Fiber Diet

  • Foods - white bread, cheese, eggs, yogurt
  • Soups - clear vegetable, chicken or beef broth
  • Vegetables - cooked without skin like mashed potatoes
  • Fruits - pureed fruits without skin like applesauce
Liquids Drink plenty of water
Medications
  • Take as usual unless otherwise instructed
  • Hold - Anti-Diarrheal Medication - Imodium, Kaopectate, Pepto-Bismol
  • Hold - Iron Tablets
  • Hold - Multivitamins
  • Hold - GLP1 Agonist Medication:
    • Dulaglutide (Trulicity)
    • Exenatide (Byetta)
    • Exenatide Extended Release (Bydureon BCise)
    • Liraglutide (Victoza)
    • Lixisenatide (Adlyxin)
    • Semaglutide (Ozempic, Wegovy, Rybelsus)
    • Tirzepatide (Mounjaro)

Pharmacy

  • Fill or buy preparation medication
  • Pick up 3 days before your procedure

1 Day Before the Procedure
Foods
  • Clear Liquid Diet
  • Soups - clear vegetable, chicken or beef broth
  • Juices - clear only without pulp
Liquids
  • Drink plenty of water
  • No alcohol
  • No red or purple colored drinks
Medications
  • Hold - Oral Diabetes Medication
  • Insulin - Take ½ the dose the entire day
  • Blood Pressure Medication - The pre-anesthesia team (PAT) will instruct you on how to take your blood pressure medications.
  • All other medications - continue as normal

Procedure Day
Foods No food or liquids the day of the procedure

Medication Instructions

Attention
Expected Symptoms Do not stop the bowel preparation
  • Abdominal Pain
  • Bloating
  • Cramps
  • Diarrhea
  • Gas
  • Nausea
Take
Generic Simethicone
or
Brand Name Gas-X
Chewable Tablets Only

Take one of the following based on the tablet strength available:

  • 80mg x 4 tabs
  • 125mg x 3 tabs
  • 250mg x 2 tabs

Chew tablets completely before taking the first dose.

First Dosage[Mango] → 10PM - 11PM
Step 1 10PM - 10:30PM
  • Mix Dose 1 pouch & 16 ounces of water
  • Drink the mixture
Step 2 10:30PM - 11PM

Drink 16 ounces of water
Take
Generic Simethicone
or
Brand Name Gas-X
Chewable Tablets Only

Take one of the following based on the tablet strength available:

  • 80mg x 4 tabs
  • 125mg x 3 tabs
  • 250mg x 2 tabs

Chew tablets completely before taking the second dose.

Second Dosage[Fruit Punch] → 4AM - 5AM
Step 1 4AM - 4:30AM
  • Mix Dose 2 Pouch A & Dose 2 Pouch B & 16 ounces of water
  • Drink the mixture
Step 2 4:30AM - 5AM

Drink 16 ounces of water

12AM
Foods No food or liquids after midnight except prep solution
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Frequently Asked Questions

How to take Plenvu for an afternoon appointment?

Take the first dose the evening before, around 4-5 PM, and the second dose 5-6 hours before your procedure, typically 10-11 PM, followed by clear liquids.

How do you prepare your bowels with Plenvu?

Follow a clear liquid diet the day before, mix each Plenvu dose with 16 ounces of water, drink it slowly, and follow with at least 32 ounces of clear liquids to ensure full cleansing.

What happens after taking Plenvu?

Expect frequent, watery bowel movements within 30 minutes to 3 hours. You may experience bloating, cramps, or nausea, but these typically improve as the prep progresses.

Why does Plenvu have 2 doses?

Two doses of PLENVU are required for a complete preparation for colonoscopy. The time interval between the two doses depends on the regimen prescribed and the planned timing of the colonoscopy procedure

How do you know Plenvu is working?

You will start to feel the effects within 2 hours of the first/second dose. It is important you do not eat after you've started drinking Plenvu; however, KEEP DRINKING CLEAR FLUIDS to prevent dehydration.