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Azulfidine - Sulfasalazine

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Azulfidine
Generic Name
Sulfasalazine
Drug Class
5-Aminosalicylate
Availability
Prescription
Manufacturer
Pfizer, Multiple generics
Indications
Ulcerative Colitis, Crohn's Disease
Type
Tablet
Doses
500 mg to 1 g orally 2-4 times daily
Route
Oral
Side Effects
Nausea, rash, headache, anemia, reversible male infertility
Interactions
May increase bleeding with anticoagulants; avoid in sulfa allergy
Overdose
Nausea, headache, rash, blood disorders.
Missed Dose
Take ASAP.
Contraindications
Salicylate allergy, GI obstruction, pediatric use.
Alternatives
Mesalamine, Olsalazine
Co-Pay Assistance Program
Available Rx
Patient Assistance Program
Available

Frequently Asked Questions

What is Sulfasalazine used for?

Sulfasalazine is applied in the management of inflammatory bowel disorders such as ulcerative colitis and Crohn ileus and rheumatoid arthritis.

How does Sulfasalazine work?

Sulfasalazine operates in a way that it suppresses the inflammation in the intestines and the joints. It is composed of anti-inflammatory substance as well as a sulfa antibiotic.

What are the common side effects of Sulfasalazine?

The most frequent side effects are nausea, headache, and gastrointestinal upsets. Liver, blood, or allergic reactions are the most serious side effects.

How should Sulfasalazine be taken?

Sulfasalazine is usually administered oral in form as a tablet. Depending on the condition you are having, your doctor will prescribe you the right dosage.

Can Sulfasalazine cause skin reactions?

No, yes, skin rashes or sensitivities can be caused by Sulfasalazine. In case it causes irritation of the skin, consult your physician.

Is Sulfasalazine safe during pregnancy?

The sulfasalazine must be administered during pregnancy when it is said to have more benefits than the risks. Ask your health care provider whether you are pregnant or you may want to become pregnant.

What should I do if I miss a dose of Sulfasalazine?

In case you forget to take the dose, you must take it immediately you remember unless it is nearly on the time of the next dose. Do not take two doses at once.

Can Sulfasalazine be used for conditions other than ulcerative colitis?

Yes, Sulfasalazine can also be taken in the Crohn disease and also as a component of rheumatoid arthritis treatment.

How effective is Sulfasalazine for treating inflammatory bowel diseases?

Sulfasalazine is also effective in the treatment of mild to moderate exacerbations of ulcerative colitis, it has the ability to sustain remission when taken on a regular basis.

Can Sulfasalazine interact with other medications?

Sulfasalazine has an ability to interact with other drugs especially those affecting the liver or kidney. Always make sure to report to your healthcare provider all the medicines you are taking.