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Velsipity - Etrasimod

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Velsipity
Generic Name
Etrasimod
Drug Class
Monoclonal Antibody (Anti-TL1A)
Availability
Prescription
Manufacturer
Arena Pharmaceuticals (Pfizer)
Indications
Ulcerative Colitis, Crohn's Disease
Type
Tablet
Doses
2 mg daily for maintenance
Route
Oral
Side Effects
Headache, constipation, fatigue
Interactions
Immunomodulator; avoid live vaccines; increased infection risk
Overdose
Limited data; monitor for infection, headache.
Missed Dose
Inject ASAP; resume schedule.
Contraindications
Severe hepatic impairment, active infection
Alternatives
Tofacitinib, Vedolizumab
Co-Pay Assistance Program
Available Rx
Patient Assistance Program
Not available

Frequently Asked Questions

What is Etrasimod used for?

Etrasimod is used to treat moderate to severe ulcerative colitis and is being studied for other inflammatory diseases like Crohn's disease and multiple sclerosis.

How does Etrasimod work?

Etrasimod works by targeting specific immune system receptors that control the movement of white blood cells, reducing inflammation in the intestines and other affected areas.

What are the common side effects of Etrasimod?

Common side effects include upper respiratory infections, headache, diarrhea, and elevated liver enzymes. Serious side effects may include heart problems.

Is Etrasimod effective in treating multiple sclerosis?

Etrasimod is still being studied for its effectiveness in treating multiple sclerosis, but early clinical trials show promise in reducing disease activity.

How should Etrasimod be taken?

Etrasimod is typically taken as an oral tablet once daily. The dosage and frequency will be prescribed by your healthcare provider based on your condition.

Can Etrasimod be used for Crohn’s disease?

Etrasimod is being researched for its potential use in treating Crohn's disease, with some early studies showing it may help control inflammation in the digestive tract.

Is Etrasimod safe during pregnancy?

Consult your doctor before using Etrasimod during pregnancy. Its safety during pregnancy has not been fully established, so it should only be used if necessary.

Can Etrasimod be combined with other medications?

Etrasimod may interact with other medications, especially those that affect the immune system. Always inform your healthcare provider of all medications you're taking.

What should I do if I miss a dose of Etrasimod?

If you miss a dose of Etrasimod, take it as soon as you remember unless it’s almost time for the next dose. Do not take two doses at once.

How long does it take for Etrasimod to show results?

It may take several weeks to notice the full effects of Etrasimod, especially in treating inflammatory conditions like ulcerative colitis.