| Brand Name | Nexium |
| Generic Name | Esomeprazole |
| Drug Class | Proton Pump Inhibitor (PPI) |
| Availability | Prescription and over-the-counter (OTC) |
| Manufacturer | AstraZeneca |
| Indications | Gastroesophageal reflux disease (GERD) Erosive esophagitis Duodenal ulcers caused by Helicobacter pylori Prevention of gastric ulcers in patients on chronic NSAID therapy Zollinger-Ellison syndrome |
| Type | Tablet |
| Doses | 20 mg or 40 mg once daily |
| Route | Oral |
| Side Effects | Headache Diarrhea Nausea Flatulence Decreased appetite Constipation Dry mouth Abdominal pain |
| Interactions | Clopidogrel (Plavix)Cilostazol (Pletal) Methotrexate (Trexall and others) Digoxin (Lanoxin) Warfarin(Invirase) Rifampin |
| Overdose | Confusion Drowsiness Blurred vision Tachycardia Nausea Sweating Flushing Headache Dry mouth |
| Missed Dose | Take as soon as remembered unless it's close to the next dose |
| Contraindications | Known hypersensitivity to esomeprazole or substituted benzimidazoles |
| Alternatives | Omeprazole Lansoprazole Pantoprazole Rabeprazole |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Esomeprazole is used to treat gastroesophageal reflux disease (GERD), stomach ulcers, and to reduce stomach acid production.
Esomeprazole works by inhibiting the proton pump in the stomach lining, which reduces the production of stomach acid and helps heal damaged tissue.
Common side effects include headache, diarrhea, and abdominal pain. Long-term use may increase the risk of fractures and low magnesium levels.
Esomeprazole is typically taken orally in tablet form, before meals. Follow your healthcare provider�s instructions for proper dosage and timing.
Esomeprazole is often used for long-term management of GERD, but its long-term use should be monitored due to potential side effects like bone fractures or vitamin B12 deficiency.
Esomeprazole is considered safe during pregnancy for short-term use. Consult your healthcare provider if you are pregnant or planning to become pregnant.
If you miss a dose, take it as soon as you remember unless it�s almost time for your next dose. Do not double up on doses.
Yes, Esomeprazole may interact with other medications, particularly those affecting stomach acid or those that require an acidic environment for absorption.
Esomeprazole may take a few days to fully reduce acid production and relieve GERD symptoms. Some patients may experience relief within a few hours.
Long-term use of Esomeprazole may increase the risk of gastrointestinal infections, such as Clostridium difficile. Regular monitoring is important.
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