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Nexium - Esomeprazole

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Nexium
Generic Name
Esomeprazole
Drug Class
Proton Pump Inhibitor (PPI)
Availability
Prescription and over-the-counter (OTC)
Manufacturer
AstraZeneca
Indications
Gastroesophageal reflux disease (GERD) Erosive esophagitis Duodenal ulcers caused by Helicobacter pylori Prevention of gastric ulcers in patients on chronic NSAID therapy Zollinger-Ellison syndrome
Type
Tablet
Doses
20 mg or 40 mg once daily
Route
Oral
Side Effects
Headache Diarrhea Nausea Flatulence Decreased appetite Constipation Dry mouth Abdominal pain
Interactions
Clopidogrel (Plavix)Cilostazol (Pletal) Methotrexate (Trexall and others) Digoxin (Lanoxin) Warfarin(Invirase) Rifampin
Overdose
Confusion Drowsiness Blurred vision Tachycardia Nausea Sweating Flushing Headache Dry mouth
Missed Dose
Take as soon as remembered unless it's close to the next dose
Contraindications
Known hypersensitivity to esomeprazole or substituted benzimidazoles
Alternatives
Omeprazole Lansoprazole Pantoprazole Rabeprazole
Co-Pay Assistance Program
Available
Patient Assistance Program
Available

Frequently Asked Questions

What is Esomeprazole used for?

Esomeprazole is used to treat gastroesophageal reflux disease (GERD), stomach ulcers, and to reduce stomach acid production.

How does Esomeprazole work?

Esomeprazole works by inhibiting the proton pump in the stomach lining, which reduces the production of stomach acid and helps heal damaged tissue.

What are the common side effects of Esomeprazole?

Common side effects include headache, diarrhea, and abdominal pain. Long-term use may increase the risk of fractures and low magnesium levels.

How should Esomeprazole be taken?

Esomeprazole is typically taken orally in tablet form, before meals. Follow your healthcare provider�s instructions for proper dosage and timing.

Can Esomeprazole be used for long-term management of GERD?

Esomeprazole is often used for long-term management of GERD, but its long-term use should be monitored due to potential side effects like bone fractures or vitamin B12 deficiency.

Is Esomeprazole safe during pregnancy?

Esomeprazole is considered safe during pregnancy for short-term use. Consult your healthcare provider if you are pregnant or planning to become pregnant.

What should I do if I miss a dose of Esomeprazole?

If you miss a dose, take it as soon as you remember unless it�s almost time for your next dose. Do not double up on doses.

Can Esomeprazole interact with other medications?

Yes, Esomeprazole may interact with other medications, particularly those affecting stomach acid or those that require an acidic environment for absorption.

How long does it take for Esomeprazole to work?

Esomeprazole may take a few days to fully reduce acid production and relieve GERD symptoms. Some patients may experience relief within a few hours.

Can Esomeprazole cause stomach infections?

Long-term use of Esomeprazole may increase the risk of gastrointestinal infections, such as Clostridium difficile. Regular monitoring is important.