| Brand Name | Kristalose, Duphalac |
| Generic Name | Lactulose |
| Drug Class | Osmotic Laxative |
| Availability | OTC |
| Manufacturer | AbbVie |
| Indications | Chronic Constipation |
| Type | Oral Solution |
| Doses | Oral: 15-30 mL once daily or as prescribed |
| Route | Oral |
| Side Effects | Bloating, gas, abdominal discomfort, diarrhea |
| Interactions | May enhance effects of lactulose-containing drugs; caution in diabetic patients |
| Overdose | Overdose may cause nausea, vomiting, diarrhea, and stomach cramps, or symptoms of low blood potassium or low blood sodium (confusion, weakness, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling). |
| Missed Dose | Take the missed dose as soon as you remember. If it's almost time for the next dose, skip the missed dose and resume your regular schedule. Do not double doses. |
| Contraindications | Low galactose diet, intestinal obstruction. |
| Alternatives | Polyethylene glycol, Sorbitol, Magnesium hydroxide |
| Co-Pay Assistance Program | OTC |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Lactulose is used to treat constipation and to reduce the amount of ammonia in the blood for people with liver disease.
Lactulose works by drawing water into the intestines, softening the stool and promoting bowel movements. It also helps reduce ammonia levels in the bloodstream by trapping ammonia in the colon.
Common side effects include bloating, gas, diarrhea, and abdominal cramps. These side effects usually decrease over time as your body adjusts.
Lactulose is typically taken orally in liquid form. The dosage will depend on the severity of constipation or liver disease, and your healthcare provider will adjust it accordingly.
Yes, Lactulose is commonly used to manage chronic constipation by softening stools and promoting regular bowel movements.
Lactulose is generally considered safe during pregnancy for short-term use. Always consult your healthcare provider before starting any new medication during pregnancy.
If you miss a dose, take it as soon as you remember unless it�s almost time for the next dose. Do not take two doses at once.
Lactulose may interact with medications that affect electrolyte balance or those used for treating liver disease. Always inform your healthcare provider about all medications you are taking.
Lactulose usually produces results within 24 to 48 hours. It may take a few days to achieve optimal effects, especially in cases of chronic constipation.
Yes, Lactulose is used to treat hepatic encephalopathy by reducing ammonia levels in the blood, which helps prevent confusion and other neurological symptoms.
