| Brand Name | Imodium |
| Generic Name | Loperamide |
| Drug Class | Guanylate Cyclase-C Agonist |
| Availability | OTC |
| Manufacturer | Johnson & Johnson |
| Indications | IBS-D (Chronic Diarrhea in IBS) |
| Type | Tablet, Capsule, Oral Solution |
| Doses | 2-4 mg orally after each loose stool (max 16 mg/day) |
| Route | Oral |
| Side Effects | Constipation, abdominal pain, nausea, dizziness |
| Interactions | Caution with CNS depressants, anticholinergics; avoid overuse |
| Overdose | Severe heart problems, CNS depression. |
| Missed Dose | Take when remembered; skip if near next. |
| Contraindications | Children under 2 years, acute dysentery, pseudomembranous colitis. |
| Alternatives | Diphenoxylate, Bismuth subsalicylate |
| Co-Pay Assistance Program | Available OTC |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Loperamide is used to treat diarrhea by slowing down the movement of the intestines, allowing for more water absorption from the stool.
Loperamide works by binding to opioid receptors in the gut, which reduces the speed of intestinal movement and allows the stool to become firmer.
Common side effects include constipation, dizziness, and abdominal discomfort.
Yes, Loperamide can be taken with or without food.
Loperamide should be used during pregnancy only if the potential benefits outweigh the risks. Consult your doctor before using it during pregnancy.
If you miss a dose, take it as soon as you remember unless it's almost time for the next dose. Do not take two doses at once.
Loperamide may interact with medications such as antibiotics or antifungal drugs. Consult your healthcare provider for a complete list of possible interactions.
Loperamide usually works within a few hours to reduce diarrhea and improve stool consistency.
Loperamide is generally not recommended for long-term use. If diarrhea persists, consult your doctor to rule out underlying conditions.
If you experience severe side effects such as constipation, bloating, or nausea, contact your doctor immediately.
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