| Brand Name | Cortenema |
| Generic Name | Hydrocortisone |
| Drug Class | Rectal Corticosteroid |
| Availability | Prescription |
| Manufacturer | Pfizer |
| Indications | Mild-to-moderate ulcerative colitis (distal disease) |
| Type | Tablet |
| Doses | 100 mg rectally, nightly |
| Route | Rectal (enema, foam) |
| Side Effects | GI upset, fluid retention, mood changes, increased infection risk |
| Interactions | May interact with anticoagulants and vaccines; watch fluid retention |
| Overdose | Overdose may cause severe digestive symptoms and electrolyte imbalances. |
| Missed Dose | If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. |
| Contraindications | Systemic fungal infections, rectal bleeding, severe colitis. |
| Alternatives | Budesonide, Prednisone, Methylprednisolone |
| Co-Pay Assistance Program | Available OTC |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Hydrocortisone is a corticosteroid used to reduce inflammation and treat conditions like arthritis, allergic reactions, skin conditions, and autoimmune diseases such as lupus.
Hydrocortisone works by suppressing the immune system and reducing the production of inflammatory chemicals in the body, which helps decrease swelling, redness, and pain.
Common side effects include weight gain, increased appetite, mood changes, and stomach irritation. Long-term use may lead to bone thinning, high blood pressure, and increased risk of infections.
Hydrocortisone can be taken orally in tablet form, applied topically as a cream, or injected, depending on the condition being treated. Follow your healthcare provider�s instructions for proper dosage and form.
Yes, Hydrocortisone cream or ointment is commonly used to treat skin rashes, eczema, and other inflammatory skin conditions by reducing inflammation and relieving itching.
Hydrocortisone should be used during pregnancy only if the benefits outweigh the risks. It is important to consult your healthcare provider before using it during pregnancy.
If you miss a dose, take it as soon as you remember unless it�s almost time for your next dose. Do not take two doses at once to make up for a missed one.
Yes, long-term use of Hydrocortisone can lead to high blood pressure, especially if used in high doses. Regular monitoring of blood pressure is recommended during long-term treatment.
Yes, Hydrocortisone can interact with other medications, including blood thinners, vaccines, and immunosuppressants. Always inform your healthcare provider about all medications you're taking.
Hydrocortisone typically starts working within hours to reduce inflammation and relieve symptoms. However, it may take a few days for full benefits, depending on the condition being treated.
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