Eosinophilic Jejunitis is the abnormal build up of eosinophils in the jejunum, the central part of the small intestine, through excessive accumulation of a type of white blood cell. This accumulation causes inflammation, swelling and damage of the intestine lining. It is also one of a number of eosinophilic enteral diseases. Symptoms can be controlled through early detection and treatment in order to prevent long-term complications.
Symptoms may vary from person to person but often include:
The exact cause isn't fully understood, but several factors can contribute:
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Eosinophilic Jejunitis is typically diagnosed through an endoscopy to examine the small intestine, tissue biopsy to count eosinophils, blood tests to measure white blood cell levels, and allergy testing to identify potential triggers.
Yes. An immune reaction to certain foods can lead to the accumulation of eosinophils in the jejunum, causing inflammation and symptoms in affected patients.
No. Eosinophilic Esophagitis affects the esophagus, while Eosinophilic Jejunitis affects the jejunum (the middle part of the small intestine), resulting in different symptoms and treatment approaches.
Steroids help reduce inflammation and relieve symptoms but are not a permanent cure. They are usually combined with dietary modifications or other medications for long-term care.
Treatment duration varies. Some patients improve within weeks, while others may require months of medication, dietary adjustments, and follow-ups to maintain improvement.
Biologics may cause injection site reactions, infections, or immune system changes. Your gastroenterologist will explain potential risks and benefits to guide treatment decisions.
Yes. Eosinophilic gastrointestinal diseases are best managed by a board-certified gastroenterologist for accurate diagnosis, tailored treatment plans, and lifelong care.
Children and teenagers can develop Eosinophilic Jejunitis. Pediatric care involves careful dietary management, monitoring growth and nutrition, and frequent consultations with specialists.
Eosinophilic Jejunitis may involve autoimmune and allergic mechanisms, where the immune system wrongly attacks the intestinal lining, leading to eosinophil accumulation.
Dietary interventions, including elimination of trigger foods, are essential. Many patients also require medications like steroids or biologics to comprehensively reduce inflammation and manage symptoms.
