Eosinophilic Jejunitis occurs when an excessive number of eosinophils-a type of white blood cell-accumulate in the jejunum, the middle section of the small intestine. This buildup triggers inflammation, swelling, and damage to the intestinal lining. It's one of several eosinophilic gastrointestinal diseases. Early detection and treatment can help control symptoms and prevent long-term complications.
Symptoms may vary from person to person but often include:
The exact cause isn't fully understood, but several factors can contribute:
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Diagnosis typically involves an endoscopy to view the small intestine, tissue biopsies to count eosinophils, blood tests to check white cell levels, and allergy evaluations to identify potential triggers.
Yes. Many patients have immune reactions to specific foods that prompt eosinophil accumulation in the jejunum and trigger inflammation and symptoms.
No. Eosinophilic Esophagitis affects the esophagus, whereas Eosinophilic Jejunitis involves the jejunum, the middle section of the small intestine, leading to different symptoms and treatment approaches.
Steroids help reduce inflammation and relieve symptoms, but they do not always offer a permanent cure. Long-term management often combines steroids with dietary changes or other medications.
Treatment duration varies. Some patients experience relief within a few weeks of therapy, while others require months of medication, diet modification, and follow-up to achieve sustained improvement.
Biologics can carry risks such as injection-site reactions, infections, or immune changes. Your gastroenterologist will discuss potential benefits and side effects to help you make an informed choice.
Yes. A board-certified gastroenterologist with experience in eosinophilic gastrointestinal diseases can provide accurate diagnosis, tailored treatment plans, and ongoing care to manage your condition effectively.
Yes. Children and adolescents can be affected. Pediatric patients often need careful dietary planning, monitoring of growth and nutrition, and regular follow-up with a specialist.
It may involve both autoimmune and allergic mechanisms. The body's immune system reacts inappropriately to food or environmental triggers, attacking the intestinal lining and causing eosinophil buildup.
Dietary changes-such as eliminating trigger foods-are a cornerstone of care, but many patients also require medications like steroids or biologics to fully control inflammation and symptoms.
