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Neuroendocrine Tumors Gastroenterologist

The NETs are rare benign tumors that form out of hormone-producing cells, typically of the gastrointestinal tract or of the pancreas. Dr. Rishi Chadha in Houston combines advanced diagnostics, procedures that are less invasive and patient-centeredness in treating NETs and improving patient outcomes.

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Rishi Chadha

About the Expert

Dr. Rishi Chadha, MD is a board‑certified gastroenterologist who specializes in preventive gastroenterology, colorectal cancer screening, and minimally invasive endoscopic procedures. He completed his fellowship at Sunrise Health GME in Las Vegas and previously trained in internal medicine at St. Vincent’s Medical Center in Connecticut.

What Are Neuroendocrine Tumors?

Neuroendocrine tumors (NETs) are rare malformations, and they start in the hormone-producing cells. These tumors can take place in the stomach, the pancreas or the intestine. Other NETs are over-producing the hormones and they may also present with different symptoms.

Common Causes and Risk Factors

  • Inherited disease: Family history of MEN1 or NETs.
  • History of smoking or excessive drinking.
  • Long-term issues of the gut or pancreas.
  • Obesity.
  • Age over 50.

Signs and Symptoms

  • Erythema or flushing of face.
  • Frequent diarrhea.
  • Belly pain or bloating.
  • Pain/difficulty breathing or wheezing.
  • Unexplained weight loss.
  • At stage 4, it may also spread to liver and bones with more severe symptoms.

How Dr. Rishi Chadha Diagnoses Neuroendocrine Tumors?

Dr. Chadha uses a step-by-step approach:

Medical History and Physical Exam

He examines your family and personal history including any genetic disease like MEN1, any lifestyle associated factor and GI or pancreatic issues in the past. A physical test examination confirms the existence of abdominal pains, lumps or abnormal hormones.

Blood and Urine Tests

Molecular tests diagnose excessively secreted hormones that could also indicate a NET and identify a deficiency of hormones in blood or 24-hour random urine samples by use of special panels serotonin, gastrin, insulin, and cortisol.

Imaging Studies

  • CT and MRI scans provide a detailed view of the pancreas, liver and intestines so as to detect and establish the size of the tumor.
  • The 68Ga-DOTATATE PET/CT is sensitive to a higher receptor activity which is highly expressed in NET cell.

Endoscopic Biopsy

A small fragment of tissue is taken away and a GI tract is looked at visually with the assistance of endoscope. Pathology is done to diagnose the type and grade of NET, hence guiding the targeted therapy.

Multidisciplinary Review

These findings are discussed with a panel of oncologists, radiologists and endocrinologists with the aim of establishing a precise diagnosis and a tailor-made treatment regimen.

Dr. Rishi Chadha
Treatment

Our Houston team offers a full range of care for neuroendocrine tumors.

1. Lifestyle and Diet Changes

  • Lifestyle and Diet Changes Eat small low-fat meals with intervals.
  • Avoid caffeine and alcohol
  • Your food ought to contain increased fiber to enable you to digest it.
  • Stay well hydrated

2. Medications

  • Delayed secretion of growth hormone by somatropins analogs.
  • Toxic therapy to delay tumor progression.
  • Antihistamine in emergency of stomach pain.
  • Demand-based anti-diarrheal and analgesic medication.

3. Minimally Invasive or Advanced Procedures

  • Microscopic tumors Endoscopic resection.
  • Laparoscopic surgical procedure of deep tumors.
  • Radiofrequency ablation of cancerous cells.
  • Peptide Receptor Radionuclide Therapy (PRRT) in its developed types.
Rishi Chadha

About the Author

Dr. Rishi Chadha, MD is a board‑certified gastroenterologist who specializes in preventive gastroenterology, colorectal cancer screening, and minimally invasive endoscopic procedures. He completed his fellowship at Sunrise Health GME in Las Vegas and previously trained in internal medicine at St. Vincent’s Medical Center in Connecticut.

What are the neuroendocrine tumors?

Neuroendocrine tumors (NETs) are rare tumors, and they start to develop in the hormone-producing cells, typically in the stomach, pancreas, intestines, or lungs.

How are NETs diagnosed?

Dr. Chadha uses a blood and urine test, imaging (CT, MRI, PET scan) and, in some cases, endoscopic biopsy as a method of confirming the diagnosis.

What are the common characteristics of NETs?

The symptoms vary with the location of the tumors and the type of secretions since it mainly entails facial flushing, frequent diarrhea, abdominal pain or bloating, wheezing and unexplainable weight loss.

What types of NETs are there?

The commonest are carcinoid tumors (that are common in the gut or lungs) and pancreatic neuroendocrine tumors (pNETs).

Can stage 4 NETs be treated?

Yes. The advanced NETs can be treated using the following methods; Peptide Receptor Radionuclide Therapy (PRRT), targeted therapy, symptomatic therapy, and palliative care.

What does the NETs treatment appear like?

Treatment may consist of lifestyle and diet modification, somatostatin analogs, targeted therapy, anti-diarrheal and analgesics, minimal invasive treatment, surgery, and PRRT based on the tumor type and stage.

Postoperative recovery after NET surgery How long?

Recovery is fast after laparoscopic removal and most of the patients improve after 1-2 weeks.

Are NETs hereditary?

Some NETs like MEN1 and family history of NETs may pose a risk of getting genetic conditions.

Do I need a special diet?

Yes. The symptoms can be controlled and digest better by eating small low-fat meals, drinking no caffeine or alcohol, consuming fibers and staying well hydrated.

How often are follow-ups done?

The visits are usually done after 3-6 months of your treatment and condition upon treatment plan and your progress.

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