Cholesterolosis occurs when cholesterol deposits accumulate in the gallbladder wall, creating small yellow flecks that can give the tissue a "strawberry" appearance on ultrasound or during surgery. Most people have no symptoms, and it is often found incidentally on imaging studies or during a gallbladder procedure.
Many individuals with cholesterolosis experience no discomfort. If symptoms do appear, you may notice:
While the precise cause isn't fully understood, several factors increase the likelihood of cholesterolosis:
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Most people don't notice any symptoms. If you do feel something, it's usually mild upper-right abdominal discomfort, bloating, nausea or indigestion after meals.
An abdominal ultrasound will show small bright (echogenic) spots on the gallbladder wall, indicating cholesterol deposits.
The ICD-10 code for cholesterolosis is K82.4.
No. Adenomyomatosis involves thickening of the gallbladder muscle layer, while cholesterolosis is due to fat (cholesterol) buildup in the gallbladder lining.
Yes. Adopting a heart-healthy diet low in saturated fats, maintaining a healthy weight and exercising regularly can support bile flow and reduce cholesterol buildup.
Hyperplastic cholesterolosis is a form where the gallbladder wall not only accumulates cholesterol but also shows an overgrowth of mucosal cells, causing a thicker, raised surface.
Most people don't. Surgery (gallbladder removal) is only recommended if you have persistent pain or develop gallstones alongside cholesterolosis.
No. Cholesterolosis is a benign condition and does not increase your risk of gallbladder cancer.
If you have symptoms or other gallbladder concerns, an ultrasound every 6-12 months is generally advised to monitor for changes.
Make an appointment if you experience ongoing upper-right abdominal pain, bloating after meals, nausea or if imaging shows new or worsening changes.