Hereditary pancreatitis is a rare, inherited disorder that causes recurrent inflammation of the pancreas. Gene mutations lead to premature activation of digestive enzymes inside the organ, resulting in repeated flare-ups, gradual tissue damage, impaired digestion, and potential blood sugar problems. Early diagnosis and management can help reduce complications and improve quality of life.
Symptoms often come and go, with episodes of acute pain interspersed with pain-free periods. Typical complaints include:
Hereditary pancreatitis is driven by inherited gene mutations that disrupt normal enzyme regulation. Key causes include:
At GastroDoxs in Houston, our hereditary pancreatitis experts deliver personalized care-from genetic counseling and enzyme therapies to targeted nutrition plans and non-opioid pain management. With board-certified gastroenterologists, same-day or next-day appointments, and a compassionate, patient-centered approach, we're here to help you control symptoms, prevent flare-ups, and maintain long-term wellness. Book your appointment today and take charge of your pancreatic health with confidence.
We've successfully treated more than 1K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.
With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Flare-ups occur when genetic mutations cause digestive enzymes to activate too early inside the pancreas, leading to inflammation, pain, and organ swelling.
Diagnosis involves a combination of genetic testing for PRSS1, SPINK1, or CFTR mutations, blood work, imaging (CT or MRI), and a thorough review of your family history.
Yes. Many cases begin in childhood or the teenage years, often presenting as recurrent abdominal pain or digestive issues.
No. Hereditary pancreatitis is chronic inflammation of the pancreas. While it can slightly increase long-term cancer risk, it is not cancer itself.
Certain pancreatic cancers can be hereditary. We help assess your personal and family risk through genetic counseling and targeted testing.
Yes. Gene mutations linked to cancer risk can be passed down through generations, so a grandparent's mutation may affect you.
Mutations in genes such as BRCA2, PALB2, and others can raise pancreatic cancer risk. Genetic counseling can determine which tests are right for you.
Call GastroDoxs to schedule an appointment with our board-certified gastroenterologists specializing in hereditary pancreatitis care and genetic counseling.
A low-fat, high-protein diet with small, frequent meals is recommended. Avoid fried foods, heavy sauces, and alcohol to reduce pain and digestive stress.
Seek immediate care if you experience severe abdominal pain, high fever, persistent vomiting, or signs of dehydration such as rapid heartbeat or dizziness.
