Eosinophilic jejunitis is a rare inflammatory condition in which eosinophils-a type of white blood cell-accumulate in the jejunum (the middle segment of the small intestine). Instead of protecting against infection, these cells trigger irritation, swelling and tissue damage. The ICD-10 code for this diagnosis is K52.81.
Symptoms may vary from person to person, but the most frequently reported include:
The exact cause is unknown, but several risk factors have been identified:
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Eosinophilic jejunitis is a rare condition in which an excess of eosinophils (a type of white blood cell) accumulates in the jejunum, causing inflammation, swelling, and digestive symptoms.
The exact cause is unknown, but common risk factors include food allergies (eggs, milk, soy), immune system dysfunction, genetic predisposition, and environmental triggers such as infections or pollutants.
Early signs often include abdominal pain or cramps, nausea, vomiting, diarrhea or loose stools, bloating, gas, and unexplained weight loss.
The official ICD-10 code for eosinophilic jejunitis is K52.81, used by healthcare providers for diagnosis and medical records.
Diagnosis typically involves an endoscopy with biopsy of the small intestine, blood tests to measure eosinophil levels, and allergy testing to identify potential food triggers.
Treatment may include dietary changes (elimination diets), corticosteroids to reduce inflammation, biologic medications for refractory cases, and endoscopic procedures like balloon dilation.
Some patients respond well to elimination diets that remove food triggers, but many require medications-such as steroids or biologics-to control inflammation and symptoms fully.
Improvement timelines vary. Some patients notice relief within a few weeks of starting treatment, while others may need several months of therapy and follow-up.
Yes. Consulting a Houston-based gastroenterologist or a specialist in eosinophilic gut disorders ensures accurate diagnosis, personalized treatment plans, and ongoing support.
GastroDoxs in Houston offers a multidisciplinary team-including gastroenterologists, dietitians, and nurse educators-providing on-site testing, personalized treatment, and comprehensive follow-up care for eosinophilic jejunitis.
