Reglan|Metoclopramide

Reglan - Metoclopramide

Medically Reviewed by Dr. Bharat Pothuri, MD, FACG

Brand Name: Reglan
Generic Name: Metoclopramide
Drug Class: Prokinetic agent; Antiemetic
Availability: Prescription only
Manufacturer: A.H. Robins
Indications: Diabetic gastroparesis Gastroesophageal reflux disease (GERD) Prevention of nausea and vomiting associated with chemotherapy or surgery Facilitation of small bowel intubation and radiologic examinations
Type: Tablet
Doses: 10 mg
Route: Oral
Side Effects: Drowsiness Fatigue Restlessness Extrapyramidal symptoms (e.g., tremors, involuntary movements) Tardive dyskinesia (with long-term use) Depression
Interactions: May enhance the effects of alcohol and other CNS depressants Can interact with antipsychotic medications, increasing the risk of extrapyramidal symptoms May affect the absorption of drugs such as digoxin and cyclosporine
Overdose: Drowsiness Disorientation Extrapyramidal reactions Seizures
Missed Dose: Take as soon as remembered unless it's close to the next dose
Contraindications: Known hypersensitivity to metoclopramide Gastrointestinal bleeding, obstruction, or perforation Pheochromocytoma History of tardive dyskinesia or other extrapyramidal symptoms
Alternatives: Domperidone (Note: Not approved in the U.S.) Erythromycin (used off-label for gastroparesis) Prochlorperazine (for nausea and vomiting)
Co-Pay Assistance Program: Available
Patient Assistance Program: Available

Frequently Asked Questions

What is Metoclopramide used for?

Metoclopramide is used to treat nausea, vomiting, and gastric stasis, and it is also used to help with conditions like gastroesophageal reflux disease (GERD).

How does Metoclopramide work?

Metoclopramide works by stimulating the muscles of the stomach and intestines, promoting gastric emptying and reducing the sensation of nausea.

What are the common side effects of Metoclopramide?

Common side effects include drowsiness, fatigue, and diarrhea. Serious side effects may include tardive dyskinesia (a movement disorder) and other neurological symptoms.

How should Metoclopramide be taken?

Metoclopramide is typically taken orally in tablet form, usually 30 minutes before meals and at bedtime. Follow your doctorï¿½s instructions for dosage and timing.

Is Metoclopramide safe during pregnancy?

Metoclopramide should be used during pregnancy only if the benefits outweigh the risks. Consult your healthcare provider if you are pregnant or planning to become pregnant.

Can Metoclopramide cause movement disorders?

Yes, long-term use of Metoclopramide can cause movement disorders such as tardive dyskinesia, especially in older adults. Regular monitoring is important.

What should I do if I miss a dose of Metoclopramide?

If you miss a dose, take it as soon as you remember unless it's almost time for the next dose. Do not take two doses at once.

Can Metoclopramide interact with other medications?

Yes, Metoclopramide can interact with medications that affect the central nervous system, including sedatives and other anti-nausea drugs. Always inform your healthcare provider about other medications you're taking.

How long does it take for Metoclopramide to work?

Metoclopramide generally works within 30 minutes to an hour of taking it, providing relief from nausea and promoting gastric emptying.

Can Metoclopramide be used for GERD?

Yes, Metoclopramide is sometimes used to treat GERD by helping to speed up the movement of food through the stomach and reduce reflux symptoms.

Reglan