| Brand Name | Reglan |
| Generic Name | Metoclopramide |
| Drug Class | Prokinetic agent; Antiemetic |
| Availability | Prescription only |
| Manufacturer | A.H. Robins |
| Indications | Diabetic gastroparesis Gastroesophageal reflux disease (GERD) Prevention of nausea and vomiting associated with chemotherapy or surgery Facilitation of small bowel intubation and radiologic examinations |
| Type | Tablet |
| Doses | 10 mg |
| Route | Oral |
| Side Effects | Drowsiness Fatigue Restlessness Extrapyramidal symptoms (e.g., tremors, involuntary movements) Tardive dyskinesia (with long-term use) Depression |
| Interactions | May enhance the effects of alcohol and other CNS depressants Can interact with antipsychotic medications, increasing the risk of extrapyramidal symptoms May affect the absorption of drugs such as digoxin and cyclosporine |
| Overdose | Drowsiness Disorientation Extrapyramidal reactions Seizures |
| Missed Dose | Take as soon as remembered unless it's close to the next dose |
| Contraindications | Known hypersensitivity to metoclopramide Gastrointestinal bleeding, obstruction, or perforation Pheochromocytoma History of tardive dyskinesia or other extrapyramidal symptoms |
| Alternatives | Domperidone (Note: Not approved in the U.S.) Erythromycin (used off-label for gastroparesis) Prochlorperazine (for nausea and vomiting) |
| Co-Pay Assistance Program | Available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Metoclopramide is used to treat nausea, vomiting, and gastric stasis, and it is also used to help with conditions like gastroesophageal reflux disease (GERD).
Metoclopramide works by stimulating the muscles of the stomach and intestines, promoting gastric emptying and reducing the sensation of nausea.
Common side effects include drowsiness, fatigue, and diarrhea. Serious side effects may include tardive dyskinesia (a movement disorder) and other neurological symptoms.
Metoclopramide is typically taken orally in tablet form, usually 30 minutes before meals and at bedtime. Follow your doctor�s instructions for dosage and timing.
Metoclopramide should be used during pregnancy only if the benefits outweigh the risks. Consult your healthcare provider if you are pregnant or planning to become pregnant.
Yes, long-term use of Metoclopramide can cause movement disorders such as tardive dyskinesia, especially in older adults. Regular monitoring is important.
If you miss a dose, take it as soon as you remember unless it's almost time for the next dose. Do not take two doses at once.
Yes, Metoclopramide can interact with medications that affect the central nervous system, including sedatives and other anti-nausea drugs. Always inform your healthcare provider about other medications you're taking.
Metoclopramide generally works within 30 minutes to an hour of taking it, providing relief from nausea and promoting gastric emptying.
Yes, Metoclopramide is sometimes used to treat GERD by helping to speed up the movement of food through the stomach and reduce reflux symptoms.
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