Eosinophilic Ileitis is a rare inflammatory disease that affects ileum (the end part of small intestine) that in turn is as a result of the excessive accumulation of eosinophils-white blood cells that facilitate allergic reactions. This build-up causes swelling, irritation and the lack of digestive ability.
You may experience symptoms that develop gradually or come and go. These include:
While the exact trigger isn't fully understood, several factors are known to contribute:
The digestive health is our priority at GastroDoxs in Katy. Our gastroenterologist board-certified physicians work in areas of diagnosis and treatment of eosinophilic ileitis through their personalized approach i.e., the diets, medication plans and nutrition support based on your needs. You will have the advantage of having on-site lab tests, endoscopy and a team of nurse leaders and dietitians who will combine their efforts to ensure that you get lasting relief.
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Diagnosis is done using blood tests to check for high eosinophil levels, stool tests to exclude infections, and an endoscopy of the ileum with biopsy to confirm eosinophil accumulation in the intestinal wall.
Unlike IBS or ulcerative colitis, Eosinophilic Ileitis is characterized by excessive infiltration of eosinophils in the terminal part of the small intestine, leading to inflammation and irritation.
Food allergens or sensitivities (such as milk, soy, wheat, and eggs) can trigger an immune response that causes eosinophil accumulation in the ileum.
Although more common in adults, children can also develop Eosinophilic Ileitis. Early identification and management are essential to prevent complications and nutritional deficiencies.
Chronic inflammation, reduced appetite, malabsorption of nutrients, or dietary restrictions for symptom management can lead to unintended weight loss.
Stress does not cause Eosinophilic Ileitis, but it may worsen symptoms such as abdominal pain, bloating, and diarrhea. Stress management can support overall treatment.
Surgery is rarely necessary. Most patients respond well to dietary modifications, anti-inflammatory drugs, or immunosuppressants. Surgical intervention is reserved for severe complications.
Some patients experience symptom relief within weeks of dietary and medical therapy, while others require ongoing management and periodic adjustments for long-term control.
Recurrence can occur if triggers are reintroduced or medication is withdrawn prematurely. Regular follow-ups are critical to monitor and address flares promptly.
Consult a board-certified gastroenterologist if you experience persistent abdominal pain, ongoing diarrhea, unexplained weight loss, or a combination of these symptoms to ensure timely diagnosis and treatment.