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Overlap Syndrome

At GastroDoxs in Houston, Dr. Scott specializes in diagnosing and managing asthma-COPD overlap syndrome-a condition presenting features of both asthma and COPD. With personalized treatment plans, advanced testing, and comprehensive support, he helps patients breathe easier and reduce flare-ups.

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Scott Liu

About the Expert

Dr. Scott Liu, MD, is a board-certified gastroenterologist with over six years of experience and a background in military medicine. He earned his medical degree from the University of Maryland, Baltimore, completed his Internal Medicine residency at Naval Medical Center Portsmouth, and finished his Gastroenterology fellowship through the National Capital Consortium. Dr. Liu provides comprehensive care for a broad range of digestive conditions, including abdominal pain, acid reflux, liver disease, chronic diarrhea, and colon cancer screening. He is a member of the American College of Gastroenterology and is known for his disciplined, patient-focused approach and clear communication.

What Is Overlap Syndrome?

Asthma-COPD overlap syndrome occurs when a person shows features of both asthma and chronic obstructive pulmonary disease. This combination often leads to more severe respiratory symptoms and a higher risk of flare-ups.

Common Causes and Risk Factors

  • Long-term exposure to cigarette smoke or air pollution
  • History of asthma or allergies in childhood
  • Frequent lung infections
  • Family history of chronic lung disease
  • Workplace exposure to dust, chemicals, or fumes
  • Age over 40 with a history of smoking

Signs and Symptoms

  • Shortness of breath, especially during activity
  • Wheezing or noisy breathing
  • Persistent cough with or without mucus
  • Chest tightness or discomfort
  • Frequent respiratory flare-ups or exacerbations

How Dr. Scott Diagnoses This Condition?

Dr. Scott uses a step-by-step approach:

Medical History and Physical Exam

He reviews your past asthma attacks, COPD symptoms, smoking history, allergy triggers, occupational or environmental exposures, and family lung‐disease background.

Spirometry with Bronchodilator Challenge

Spirometry measures how much air you can inhale and exhale. After a bronchodilator is given, repeat testing shows whether your airway obstruction reverses-key to distinguishing asthma from COPD features.

Blood Tests

He checks blood eosinophil counts and IgE levels to gauge allergic inflammation. In select patients, alpha-1 antitrypsin levels are measured if early or atypical COPD is suspected.

Imaging Studies

  • Chest X-ray to exclude infections, tumors, or other lung conditions.
  • High-resolution CT scan to evaluate airway wall thickening, emphysema, and overall lung architecture.

Advanced Pulmonary Testing (If Needed)

For complex cases, lung volume measurements, diffusion capacity (DLCO) tests, or bronchial provocation (methacholine challenge) may be performed to refine the overlap syndrome diagnosis.

Dr. Scott
Treatment

Our Team offers a full range of care for asthma-COPD overlap syndrome.

1. Lifestyle and Diet Modifications

  • Quit smoking and avoid secondhand smoke
  • Exercise regularly with safe activities like walking or swimming
  • Eat a healthy diet rich in fruits, vegetables, and whole grains
  • Get annual flu and pneumonia vaccinations

2. Medications

  • Inhaled corticosteroids to reduce airway inflammation
  • Long-acting bronchodilators to improve airflow
  • Rescue inhalers for quick relief
  • Combination inhalers for long-term symptom control

3. Minimally Invasive or Advanced Procedures

  • Lung procedures to reduce trapped air
  • Pulmonary rehabilitation programs for comprehensive breathing support
  • Oxygen therapy for patients with low oxygen levels
Scott Liu

About the Expert

Dr. Scott Liu, MD, is a board-certified gastroenterologist with over six years of experience and a background in military medicine. He earned his medical degree from the University of Maryland, Baltimore, completed his Internal Medicine residency at Naval Medical Center Portsmouth, and finished his Gastroenterology fellowship through the National Capital Consortium. Dr. Liu provides comprehensive care for a broad range of digestive conditions, including abdominal pain, acid reflux, liver disease, chronic diarrhea, and colon cancer screening. He is a member of the American College of Gastroenterology and is known for his disciplined, patient-focused approach and clear communication.

Frequently Asked Questions

What is asthma-COPD overlap syndrome?

It's when a person has features of both asthma and COPD. This overlap often causes more severe breathing problems if not treated properly.

Does it affect how long I will live?

With early care and adherence to your treatment plan, most people live full, active lives. Avoiding flare-ups and following Dr. Scott's guidance are key.

What diagnosis code is used?

Doctors commonly use ICD-10 codes J45 for asthma and J44.9 for COPD when recording overlap syndrome.

Can the lung damage be reversed?

Permanent scarring cannot be undone, but treatment can greatly improve lung function, reduce symptoms, and enhance quality of life.

How often should I see Dr. Scott?

Routine visits are usually every 3 to 6 months. You may need more frequent follow-ups during flare-ups or medication adjustments.

Are vaccines really necessary?

Yes. Annual flu and pneumonia vaccines help prevent serious lung infections and reduce the risk of severe exacerbations.

Will I need oxygen?

Some patients require supplemental oxygen during sleep or activity. Dr. Scott will test your oxygen levels before making any recommendations.

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