Alpha 1 Anti trypsin Deficiency (AATD) is a symptom inherited disorder and it is caused due to the insufficient production of the protective protein alpha-1 antitrypsin. The insufficient amount of this protein may cause destruction of lung tissue in the long run and non-functional protein proceeds to accumulate in the liver resulting to dysfunction of the organs.
The AATD symptoms are not so obvious, however, as the disease advances, you can observe:
AATD is produced as a result of hereditary mutations of SERPINA1 gene. Key points include:
The specialists of our Alpha 1 Anti-Trypsin department at gastro dosx at Cypress will be specialized in offering personalized and holistic services to the health of the lungs and liver. We do it one step at a time, and you, as expedited genetic tests and definitive diagnosis, as an individual plan of treatment and support. Wait-book-your-appointment Not wait-book-your-appointment this day and experience the best that AATD has to offer you, with the professionals in mind, in the neighborhood of your home.
We've successfully treated more than 1.5K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.
With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Alpha 1 Anti Trypsin Deficiency is a genetic illness in which the body fails to produce enough of A1AT protein which ultimately leads to destruction of the lungs and liver.
The typical symptoms are the shortness of breath, coughing and wheezing, numerous chest infections, jaundice (yellowing of the skin or eyes), abdominal pain, or swelling and chronic fatigue.
Diagnosis is undertaken through blood tests in order to determine the concentration of the A1AT or a cheek swab to determine genetic mutation of SERPINA1 gene mutation.
Yes. Lack of A1AT protein may accumulate into the liver and inflame the liver leading to fibrosis, cirrhosis or liver failure under no treatment.
The typical AATD symptoms, including difficulties in breathing, recurrent infections and speedy lung destruction are likely to dominate among the AATD sufferers especially in the event the sufferers are smokers.
Yes. AATD results in the formation of lung damage at a faster and inferior rates and to a greater extent in smokers.
They are treated through inhalers or bronchodilators, oxygen administration, and preservation of the lung (augmentation therapy) through A1AT protein infusion. Treatment may be administered to the liver through routine check ups, feeds and symptomatic drugs.
To avoid serious complications, it is suggested that an AATD specialist visits them as soon as possible with an unexplainable result of lungs or liver, or abnormal A1AT test.
Absolutely. Quitting of smoking, eating well, moderate exercise and good health will slow disease and increase the lifespan.
GastroDoxs in Cypress provides AATD, rapid test and diagnosis, personal care of course and full support of the lung and liver health to the local professionals.
