| Brand Name | Resolor |
| Generic Name | Prucalopride |
| Drug Class | Mu-Opioid Receptor Agonist |
| Availability | Prescription |
| Manufacturer | Takeda Pharmaceuticals |
| Indications | Irritable Bowel Syndrome with Constipation (IBS-C) |
| Type | Tablet |
| Doses | 2 mg orally once daily |
| Route | Oral |
| Side Effects | Headache, diarrhea, nausea, abdominal pain |
| Interactions | Minimal interaction; may enhance GI motility; caution with other laxatives |
| Overdose | Headache, diarrhea, nausea in overdose. |
| Missed Dose | Take missed dose ASAP. |
| Contraindications | Bowel obstruction, Crohn’s disease, ulcerative colitis. |
| Alternatives | Lubiprostone, Linaclotide, Tegaserod |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Prucalopride is used to treat chronic constipation by stimulating bowel movements.
Prucalopride works by activating serotonin receptors in the gastrointestinal tract, stimulating bowel movements and improving constipation symptoms.
Common side effects include headache, nausea, abdominal discomfort, and diarrhea.
Yes, Prucalopride can be taken with or without food.
Prucalopride should only be used during pregnancy if the potential benefit justifies the risk. Consult your doctor before using it during pregnancy.
If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take two doses at once.
Prucalopride typically begins to work within 24-48 hours to relieve constipation.
Prucalopride can be used long-term for chronic constipation under the supervision of your healthcare provider.
Prucalopride has minimal interactions with other medications but should be discussed with your doctor if you're taking medications for other gastrointestinal conditions.
If you experience severe side effects such as diarrhea or abdominal pain, contact your doctor immediately.
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