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Resolor - Prucalopride

Bharat Pothuri Medically Reviewed by Dr. Bharat Pothuri, MD, FACG
Brand Name
Resolor
Generic Name
Prucalopride
Drug Class
Mu-Opioid Receptor Agonist
Availability
Prescription
Manufacturer
Takeda Pharmaceuticals
Indications
Irritable Bowel Syndrome with Constipation (IBS-C)
Type
Tablet
Doses
2 mg orally once daily
Route
Oral
Side Effects
Headache, diarrhea, nausea, abdominal pain
Interactions
Minimal interaction; may enhance GI motility; caution with other laxatives
Overdose
Headache, diarrhea, nausea in overdose.
Missed Dose
Take missed dose ASAP.
Contraindications
Bowel obstruction, Crohn disease, ulcerative colitis.
Alternatives
Lubiprostone, Linaclotide, Tegaserod
Co-Pay Assistance Program
Available Rx
Patient Assistance Program
Available

Frequently Asked Questions

What is Prucalopride used for?

Prucalopride is used to treat chronic constipation by stimulating bowel movements.

How does Prucalopride work?

Prucalopride works by activating serotonin receptors in the gastrointestinal tract, stimulating bowel movements and improving constipation symptoms.

What are the common side effects of Prucalopride?

Common side effects include headache, nausea, abdominal discomfort, and diarrhea.

Can Prucalopride be taken with food?

Yes, Prucalopride can be taken with or without food.

Is Prucalopride safe during pregnancy?

Prucalopride should only be used during pregnancy if the potential benefit justifies the risk. Consult your doctor before using it during pregnancy.

What should I do if I miss a dose of Prucalopride?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take two doses at once.

How long does it take for Prucalopride to work?

Prucalopride typically begins to work within 24-48 hours to relieve constipation.

Can Prucalopride be used long-term?

Prucalopride can be used long-term for chronic constipation under the supervision of your healthcare provider.

Can Prucalopride interact with other medications?

Prucalopride has minimal interactions with other medications but should be discussed with your doctor if you're taking medications for other gastrointestinal conditions.

What should I do if I experience side effects from Prucalopride?

If you experience severe side effects such as diarrhea or abdominal pain, contact your doctor immediately.