Pancreatic Divisum is a congenital condition in which the two main pancreatic ducts fail to fuse during fetal development, leaving separate drainage channels. In most people, these ducts join before emptying into the small intestine, but in Pancreatic Divisum they remain separate. This anatomic variation is usually harmless and often discovered incidentally on imaging studies such as MRCP or CT scans, though it can sometimes lead to impaired pancreatic drainage and pancreatitis.
Many individuals with Pancreatic Divisum experience no symptoms. When problems do occur, they may include:
Pancreatic Divisum is present at birth and results from a developmental anomaly in the pancreas. Key factors include:
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Pancreatic Divisum occurs in about 5-10% of the population, making it one of the most frequent congenital variants of pancreatic duct anatomy.
No. Most individuals remain asymptomatic and require no intervention. Treatment is only recommended for those experiencing pain or recurrent pancreatitis.
Diagnosis is made through imaging studies such as MRCP (Magnetic Resonance Cholangiopancreatography), CT scan, or ERCP, which clearly show the ductal separation.
The ductal anatomy is the same, but adults may be more likely to develop symptoms like pancreatitis or chronic abdominal pain over time compared to children.
There is no cure to alter the duct configuration. However, symptoms can be effectively managed with endoscopic therapy, medications, dietary changes, and, in rare cases, surgery.
Yes. ERCP carries risks such as post-procedure pancreatitis, infection, bleeding, and perforation. These risks are minimized when performed by experienced specialists.
A low-fat diet with small, frequent meals, adequate hydration, and, if prescribed, pancreatic enzyme supplements can help alleviate symptoms and improve digestion.
Yes. Although rare, Pancreatic Divisum can coexist with an annular pancreas, potentially worsening ductal obstruction and increasing the risk of pancreatitis.
You should consult a gastroenterologist if you experience repeated upper abdominal pain, unexplained bouts of pancreatitis, or ongoing digestive issues despite standard care.
You can contact GastroDoxs for a referral to board-certified pancreatic specialists, or ask your primary care physician for recommendations in your area.
