Nonalcoholic steatohepatitis (NASH) is a progressive form of fatty liver disease not related to alcohol consumption. In NASH, excess fat in liver cells leads to inflammation and liver cell injury. Over time, this can result in fibrosis (scarring), cirrhosis, and even liver failure if not managed.
Early stages of NASH often have no noticeable signs. As the condition advances, you may experience:
NASH is linked to several metabolic and lifestyle factors, including:
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Nonalcoholic steatohepatitis (NASH) is a form of fatty liver disease where excess fat and inflammation damage liver cells, and it occurs in people who drink little to no alcohol.
Diagnosis typically involves blood tests to check liver enzymes, imaging studies such as ultrasound or MRI to assess fat buildup, and sometimes a liver biopsy to evaluate inflammation and fibrosis.
While no drugs are yet FDA-approved specifically for NASH, several investigational therapies are available through clinical trials, and some off-label medications may be recommended to manage related conditions.
Yes. A balanced, calorie-controlled diet, regular physical activity, and sustained weight loss can reduce liver fat, improve inflammation, and slow disease progression.
Children-especially those with obesity, type 2 diabetes, or fatty liver on imaging-can develop NASH. Early detection and lifestyle intervention are key to preventing long-term complications.
Call GastroDoxs in Katy or visit our website to schedule an appointment. Our gastroenterologists and liver specialists have extensive experience in diagnosing and treating NASH.
Genetics can influence susceptibility-family history of fatty liver disease raises risk-but diet, activity level, and metabolic health also play crucial roles.
Yes. Insulin resistance and type 2 diabetes are major risk factors for NASH, as they promote fat accumulation and inflammation in the liver.
Untreated NASH can progress to liver fibrosis, cirrhosis, liver failure, and increase the risk of hepatocellular carcinoma (liver cancer).
In early stages, significant weight loss through diet and exercise may reverse fat deposition and inflammation, but more advanced fibrosis often requires additional medical or procedural interventions.
