Hirschsprung's Disease is a congenital condition in which a segment of the large intestine is born without the nerve cells (ganglion cells) needed to push stool through the colon. Without these nerves, the affected bowel cannot contract properly, causing stool to build up, the colon to dilate, and, if untreated, serious complications like enterocolitis or perforation.
Symptoms often appear in the newborn period but can sometimes present later in infancy or childhood. Key signs include:
Hirschsprung's Disease arises during fetal development when nerve cells fail to migrate into a portion of the colon. Several factors can contribute:
At GastroDoxs in Katy, our experienced team specializes in diagnosing and treating Hirschsprung's Disease with a patient-centered approach. From advanced imaging and biopsy techniques to expert surgical care and personalized follow-up, we're committed to guiding your child (or adult patient) toward lasting relief and healthy bowel function. Don't wait-book your appointment now and give your family the confident, compassionate care they deserve.
We've successfully treated more than 1.5K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.
With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Diagnosis typically involves a thorough physical exam, an abdominal X-ray with contrast (contrast enema), and confirmation with a rectal biopsy to check for missing nerve cells.
In some cases, a prenatal ultrasound may suggest abnormalities such as a distended bowel, but a definitive diagnosis is made after birth using imaging and biopsy.
There are two main types: short-segment (only the distal colon is affected) and long-segment (a larger portion of the colon lacks nerve cells). The type is determined by how much bowel is involved.
No. While severe or persistent constipation in a newborn can be a red flag, most constipation has other causes. A doctor will evaluate symptoms and may perform tests if Hirschsprung's is suspected.
Most patients stay in the hospital for 1-2 weeks post-surgery. Full recovery, including gradual return to normal diet and activities, can take several months.
No. Surgical removal of the aganglionic (nerve-free) segment is the only cure. Supportive care-like diet management-helps, but cannot replace surgery.
Untreated, it can lead to dangerous bowel obstruction, severe infection, or enterocolitis (life-threatening inflammation of the colon).
No. The condition does not resolve on its own. However, after appropriate surgery, most children achieve normal bowel function and healthy growth.
Not always. A temporary colostomy may be needed if there's severe inflammation or infection. Many patients proceed directly to a pull-through procedure without colostomy.
The GastroDoxs team in Katy offers specialized evaluation, advanced surgical techniques, and long-term follow-up for children and adults with Hirschsprung's Disease.
