Primary Sclerosing Cholangitis (PSC) is a chronic liver disorder in which the bile ducts inside and outside the liver become inflamed, scarred, and narrowed. Over time, blocked bile flow can lead to progressive liver damage, cirrhosis, and complications such as bile duct infections or liver failure. PSC is often associated with inflammatory bowel disease, particularly ulcerative colitis, but it can also occur independently.
PSC may progress slowly, and early on you might not notice any signs. As the disease advances, watch for:
The exact cause of PSC is not fully understood, but several factors appear to play a role:
Our Jersey Village team specializes in Primary Sclerosing Cholangitis care-offering expert diagnostics, personalized treatment plans, and ongoing support under one roof. From advanced imaging (MRCP/ERCP) to medical management and transplant coordination, we're dedicated to preserving your liver function and improving your quality of life.
Don't wait to safeguard your liver health. Schedule your consultation with our board-certified gastroenterologist at GastroDoxs in Jersey Village today, and get the focused, compassionate care you deserve.
We've successfully treated more than 286 patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.
With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
PSC and PBC are both chronic liver diseases of the bile ducts. PSC causes inflammation and scarring of both large and small ducts and is more common in men, whereas PBC primarily affects small intrahepatic ducts and occurs more often in women.
Yes. Approximately 70% of PSC patients also have ulcerative colitis, so it's important to screen for and manage both conditions in tandem.
PSC is not directly inherited, but certain genetic factors-such as HLA-B27-can increase your risk. Family history of autoimmune diseases may also play a role.
PSC diagnosis involves abnormal liver function tests, serologic markers, and imaging studies like MRCP or ERCP, which visualize bile duct narrowing and scarring.
Radiologic exams (MRCP or ERCP) reveal strictures, beading, and dilatation of bile ducts, helping to confirm PSC and monitor disease progression.
Treatment includes ursodeoxycholic acid to improve bile flow, endoscopic dilation of strictures via ERCP, immunosuppressive or anti-inflammatory drugs, and liver transplant for advanced disease.
Yes. Avoiding alcohol, following a balanced diet, exercising regularly, and receiving recommended vaccinations can support liver health and overall well-being.
Routine follow-up every 6-12 months is typical, though more frequent visits may be needed if symptoms worsen or complications arise.
PSC progresses slowly in many patients. Early diagnosis and appropriate management can preserve liver function, improve quality of life, and delay complications.
GastroDoxs in Jersey Village offers experienced gastroenterologists specializing in PSC. Book an appointment for comprehensive evaluation, imaging, and personalized care.
