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Neuroendocrine Tumors

Neuroendocrine tumors (NETs) arise from hormone-producing cells in organs like the gut, pancreas and lungs. Dr. Scott at GastroDoxs in Houston offers expert diagnosis and personalized treatment-ranging from medications and minimally invasive procedures to dietary and lifestyle guidance-for improved outcomes.

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Scott Liu

About the Expert

Dr. Scott Liu, MD, is a board-certified gastroenterologist with over six years of experience and a background in military medicine. He earned his medical degree from the University of Maryland, Baltimore, completed his Internal Medicine residency at Naval Medical Center Portsmouth, and finished his Gastroenterology fellowship through the National Capital Consortium. Dr. Liu provides comprehensive care for a broad range of digestive conditions, including abdominal pain, acid reflux, liver disease, chronic diarrhea, and colon cancer screening. He is a member of the American College of Gastroenterology and is known for his disciplined, patient-focused approach and clear communication.

What Are Neuroendocrine Tumors?

Neuroendocrine tumors (NETs) are rare growths that arise from neuroendocrine cells, which are found throughout the body and help control various bodily functions by releasing hormones. These tumors can develop in the gastrointestinal tract, pancreas, or lungs, and may be benign or malignant. Symptoms vary depending on the tumor's location and whether it produces hormones, and can include abdominal pain, diarrhea, flushing, or unexplained weight loss. Diagnosis often involves blood and urine tests, advanced imaging, and biopsy. Treatment options include surgery, hormone therapy, targeted drugs, and peptide receptor radionuclide therapy (PRRT), with care tailored to tumor type and stage. Early detection improves outcomes significantly.

Common Causes and Risk Factors

  • Family history of inherited syndromes (e.g., MEN1)
  • Age over 50 years
  • Slight female predominance
  • Chronic gastrointestinal inflammation (gastritis, pancreatitis)
  • Smoking (associated with pulmonary NETs)

Signs and Symptoms

  • Abdominal pain or cramping
  • Unexplained weight loss
  • Flushing or redness of the skin
  • Diarrhea or changes in bowel habits
  • Episodes of low blood sugar (hypoglycemia)
  • Wheezing or shortness of breath

How Dr. Scott Diagnoses This Condition?

Dr. Scott uses a step-by-step approach:

Medical History and Exam

He discusses your epigastric pain patterns, hormone related symptoms (flushing, diarrhea, hypoglycemia), and family history of NETs, then performs a targeted physical exam.

Lab Tests

Blood and urine assays measure tumor markers and hormone levels-chromogranin A, gastrin, insulin, and 5-HIAA-to detect functional NETs.

Imaging Studies

  • Contrast enhanced CT or MRI locates lesions in the pancreas, gut, liver, or lungs.
  • Somatostatin receptor PET/CT (e.g., DOTATATE PET) highlights small or metastatic tumors.

Advanced Testing (if needed)

Endoscopic ultrasound with fine needle aspiration or endoscopic biopsy provides tissue confirmation and grading.

Dr. Scott
Treatment

Our Team offers a full range of care for neuroendocrine tumors.

1. Lifestyle and Diet Changes

  • Eat a low-fat, high-fiber diet
  • Try small, frequent meals to prevent hormone spikes
  • Drink plenty of fluids
  • Use stress-relief tools like meditation or breathing exercises

2. Medications

  • Somatostatin analogs to slow tumor growth and control hormone levels
  • Targeted therapies aimed at specific tumor types
  • Chemotherapy for faster-growing or advanced NETs

3. Minimally Invasive and Advanced Procedures

  • Endoscopic resection to remove small tumors from the GI tract
  • Radiofrequency ablation to destroy liver tumors using heat
  • Peptide Receptor Radionuclide Therapy (PRRT) delivering radiation directly to NET cells
Scott Liu

About the Expert

Dr. Scott Liu, MD, is a board-certified gastroenterologist with over six years of experience and a background in military medicine. He earned his medical degree from the University of Maryland, Baltimore, completed his Internal Medicine residency at Naval Medical Center Portsmouth, and finished his Gastroenterology fellowship through the National Capital Consortium. Dr. Liu provides comprehensive care for a broad range of digestive conditions, including abdominal pain, acid reflux, liver disease, chronic diarrhea, and colon cancer screening. He is a member of the American College of Gastroenterology and is known for his disciplined, patient-focused approach and clear communication.

Frequently Asked Questions

Are neuroendocrine tumors cancer?

Some NETs grow slowly and act like benign tumors, while others can be malignant and spread if not treated.

What types of NETs are common?

The most common NETs are carcinoid tumors in the gut and lungs, as well as pancreatic neuroendocrine tumors.

How soon will I feel better after starting treatment?

Many patients notice symptom relief within a few weeks of beginning therapy.

Will I need surgery to treat my NET?

Not always. Small tumors can often be managed with medications or removed via minimally invasive procedures.

Can lifestyle changes really help with NET symptoms?

Yes. A balanced, low-fat diet, small frequent meals, proper hydration, and stress management can reduce symptoms.

Can NETs come back after treatment?

They can recur, which is why regular follow-up visits and imaging studies are essential.

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