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NSAID Enteritis

NSAID enteritis occurs when common pain relievers like ibuprofen and naproxen damage and inflame your small intestine. At GastroDoxs in Houston, Dr. Nghia Nguyen offers comprehensive expert diagnosis, personalized treatment plans, and advanced procedures to restore your gut health effectively.

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Texas Medical Board
Harris County Medical Society
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American Society for Gastrointestinal Endoscopy
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Houston Methodist leading Medicine
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Nghia Nguyen

About the Expert

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Common Causes and Risk Factors

  • Frequent NSAID use - taking ibuprofen, naproxen or diclofenac daily or in high doses for weeks to months
  • Age over 60 - older adults have reduced mucosal defenses
  • Medical history - previous ulcers or chronic bowel conditions
  • Lifestyle habits - smoking and heavy alcohol intake that worsen gut injury

Signs and Symptoms

  • Abdominal pain or cramping, often around the belly button
  • Diarrhea, sometimes containing blood or mucus
  • Bloating and excessive gas
  • Unintended weight loss
  • Fatigue and weakness from poor nutrient absorption

How Dr. Nghia Nguyen Diagnoses This Condition?

Dr. Nguyen uses a step-by-step approach:

Medical History and Physical Exam

He reviews your symptoms, NSAID use history, prior gut conditions and risk factors, then gently examines your abdomen for tenderness, bloating, or other signs of inflammation.

Laboratory Tests

Blood tests check for anemia, elevated inflammatory markers, and nutrient deficiencies. Stool studies look for hidden bleeding or infection.

Imaging Studies

  • Capsule Endoscopy - A swallowable camera captures detailed images of the small intestine lining to spot ulcers or bleeding.
  • CT Enterography - Provides high-resolution scans of intestinal wall thickening and inflammation.

Endoscopic Evaluation (if needed)

An upper endoscopy or device-assisted enteroscopy allows direct visualization and biopsy of affected segments to confirm diagnosis and rule out other causes.

Dr. Nghia Nguyen
Treatment

Our Team offers a full range of care for NSAID enteritis.

1. Lifestyle and Diet Changes

  • Stop or reduce NSAID use under Dr. Nguyen's guidance
  • Eat small, low-fiber meals during flare-ups
  • Stay hydrated and maintain electrolyte balance
  • Avoid smoking and limit alcohol intake

2. Medications

  • Proton pump inhibitors to reduce acid and protect the gut lining
  • Sucralfate or misoprostol to promote mucosal healing
  • Probiotics to support healthy gut bacteria

3. Minimally Invasive Procedures

  • Endoscopic hemostasis using clips or thermal therapy to stop bleeding
  • Stricture dilation to open narrowed sections of the small intestine
  • Capsule endoscopy to monitor healing and detect new areas of damage
Dr Nghia Nguyen

About the Author

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Frequently Asked Questions

What causes NSAID enteritis?

Frequent or high-dose NSAID use can damage the small intestine lining, leading to inflammation and injury.

When do symptoms start?

Symptoms often appear after weeks to months of regular NSAID use, though timing varies based on dosage and individual risk factors.

Can I stop NSAIDs right away?

Talk to Dr. Nguyen before stopping. He'll guide you through tapering or switching to safer pain-relief options.

Is this condition permanent?

No. With proper medical treatment and lifestyle adjustments, the intestine can heal and inflammation can resolve.

Will I need surgery?

Most patients improve with medications and minimally invasive procedures. Surgery is rarely required except in severe complications.

Are there over-the-counter treatments?

OTC antacids or PPIs may relieve mild symptoms temporarily, but full recovery requires a tailored treatment plan from Dr. Nguyen.

How can I prevent NSAID enteritis in the future?

Use the lowest effective NSAID dose for the shortest time. Dr. Nguyen can recommend alternative therapies and protective strategies.

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