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Eosinophilic Ileitis

Persistent abdominal cramps, diarrhea, and unexplained weight loss could signal eosinophilic ileitis—a rare small intestine inflammation. At Houston's GastroDoxs, Dr. Nguyen provides expert, compassionate care. Using advanced diagnostics and personalized treatments, he helps patients regain comfort and restore digestive health.

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Nghia Nguyen

About the Expert

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

What Is Eosinophilic Ileitis?

Eosinophilic ileitis is a rare inflammatory disorder in which eosinophils—a type of white blood cell—accumulate in the ileum, the last segment of the small intestine. Instead of fighting infection, these cells trigger swelling and irritation, leading to persistent digestive discomfort.

Common Causes and Risk Factors

  • Food or environmental allergies
  • An overactive immune response
  • Infections by certain parasites or bacteria
  • Family history of asthma, eczema, or food sensitivities

Signs and Symptoms

  • Abdominal pain or cramps
  • Diarrhea or loose stools
  • Nausea and/or vomiting
  • Unexplained weight loss
  • Fatigue or signs of poor nutrition

How Dr. Nghia Nguyen Diagnoses This Condition?

Dr. Nguyen uses a step-by-step approach:

Medical History and Exam

She reviews your abdominal and epigastric pain patterns, dietary history, known allergies, and any family history of GI or immune disorders.

Blood Tests

We measure your eosinophil count and other inflammatory markers to identify abnormal elevations.

Imaging Studies

  • CT scan or abdominal ultrasound to assess the ileum for thickening, edema, or other signs of inflammation.

Endoscopy with Biopsy

An upper endoscopy or small-bowel enteroscopy lets us visualize the lining and obtain a tissue sample. Pathology confirms eosinophil infiltration, securing the diagnosis.

Dr. Nghia Nguyen
Treatment

Our Team offers a full range of care for eosinophilic ileitis.

1. Diet and Lifestyle Changes

  • An elimination diet to identify and remove food triggers
  • Smaller, more frequent meals to ease intestinal stress
  • Targeted supplements to correct nutrient deficiencies

2. Medications

  • Steroids to rapidly reduce intestinal inflammation
  • Biologics to calm an overactive immune response
  • Proton pump inhibitors (PPIs) to control excess stomach acid

3. Minimally Invasive or Advanced Procedures

  • Endoscopic dilation to widen narrowed sections of the ileum
  • On-site advanced endoscopy for precise diagnosis and treatment
  • Minimally invasive interventions to restore healthy gut function
Dr Nghia Nguyen

About the Author

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Frequently Asked Questions

What causes eosinophilic ileitis?

It is often caused by allergies, immune system overactivity, or certain infections that lead to eosinophil buildup in the ileum.

How is eosinophilic ileitis treated at GastroDoxs?

Dr. Nguyen combines targeted diet changes, medications like steroids or biologics, and minimally invasive procedures when necessary to control inflammation and symptoms.

Can eosinophilic ileitis be cured?

There is no definitive cure, but most patients experience significant relief and improved quality of life with Dr. Nguyen's comprehensive care plan.

Will the eosinophil buildup ever go away completely?

While eosinophil levels may fluctuate, ongoing treatment and monitoring help keep inflammation under control and minimize flare-ups.

When should I see a doctor for persistent belly pain?

If your abdominal pain is severe, lasts more than a few days, or is accompanied by unexplained weight loss or nutritional issues, schedule an evaluation promptly.

Is eosinophilic ileitis a serious condition?

Yes, it can lead to complications if untreated. Early diagnosis and personalized treatment from Dr. Nguyen help you feel better and maintain gut health.

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