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Eosinophilic Gastritis

Eosinophilic gastritis is a rare immune-driven disorder marked by stomach lining inflammation from excess eosinophils. At GastroDoxs in Houston, Dr. Bharat Pothuri offers personalized diagnosis-including endoscopy and allergy testing-and tailored treatments such as dietary plans, medications, and scopes for relief.

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Bharat Pothuri

About the Expert

Dr. Bharat Pothuri is a board-certified gastroenterologist and the founder of GastroDoxs. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

What Is Eosinophilic Gastritis?

Eosinophilic gastritis is a rare inflammatory disorder in which eosinophils (a type of white blood cell) accumulate in the stomach lining. Under normal conditions, eosinophils help fight infections, but excessive buildup causes swelling, tissue damage, and a range of digestive symptoms.

Common Causes and Risk Factors

  • Food allergies (dairy, wheat, soy, nuts, eggs)
  • Personal or family history of allergic conditions (asthma, eczema, allergic rhinitis)
  • Other eosinophilic gastrointestinal disorders (e.g., eosinophilic esophagitis)
  • Immune system dysfunction or hypersensitivity
  • Genetic predisposition affecting immune regulation

Signs and Symptoms

  • Upper abdominal pain or cramping, often after meals
  • Nausea and vomiting
  • Acid reflux or heartburn
  • Early satiety (feeling full after small amounts of food)
  • Bloating and abdominal distension
  • Diarrhea
  • Unintentional weight loss
  • Fatigue or nutrient deficiencies (in prolonged cases)

Expert Treatment for Eosinophilic Gastritis by Dr. Bharat Pothuri

Dr. Pothuri uses a step-by-step approach:

Medical History and Physical Exam

He reviews your symptom timeline, dietary habits, allergy history (asthma, eczema), and any family history of eosinophilic or allergic disorders.

Blood Tests

We measure peripheral eosinophil counts, check for elevated IgE levels, and rule out parasitic or infectious causes of eosinophilia.

Allergy Evaluation

  • Skin-prick testing or serum-specific IgE panels identify common food triggers (dairy, wheat, soy).
  • Patch testing may detect delayed hypersensitivity reactions.

Upper Endoscopy with Biopsy

An endoscope examines the stomach lining directly. Targeted biopsies are taken to confirm eosinophil infiltration and grade the severity of inflammation.

Imaging Studies (if needed)

  • Abdominal ultrasound or CT scan to assess wall thickening or rule out other structural abnormalities.
  • MRI enterography in select cases to evaluate deeper layers of the stomach and adjacent structures.
Bharat Pothuri
Treatment

Our Team offers a full range of care for eosinophilic gastritis.

1. Diet and Lifestyle Modifications

  • Elimination diets guided by a registered dietitian to identify triggers (dairy, wheat, soy, etc.)
  • Personalized meal plans to reduce stomach inflammation and improve digestion
  • Step-wise food reintroduction and ongoing nutritional counseling

2. Medications

  • Acid-reducing agents (PPIs, H2 blockers) to relieve pain and reflux
  • Topical or systemic corticosteroids to decrease eosinophilic swelling
  • Biologic therapies targeting specific immune pathways in more severe cases

3. Minimally Invasive Procedures

  • Upper endoscopy with biopsy for precise diagnosis and monitoring
  • Endoscopic dilation to treat strictures or narrowing without surgery
  • Endoscopic removal of small growths or polyps if detected
1.5K

Patients Treated

Dr. Pothuri has treated more than 1.5K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.

20Y

Years of Experience

With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients

Bharat Pothuri

About the Author

Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

Frequently Asked Questions

What causes eosinophilic gastritis?

Food allergies and immune system dysfunction are the most common triggers. A personal or family history of asthma, eczema, or other allergic conditions can also increase risk.

How is it diagnosed?

Diagnosis combines blood tests for elevated eosinophils, allergy testing, and an upper endoscopy with biopsy to confirm eosinophil infiltration in the stomach lining.

Can diet help on its own?

Sometimes yes. Eliminating trigger foods under a dietitian's guidance can relieve symptoms, but many patients also require medication to fully control inflammation.

Is it the same as eosinophilic esophagitis?

No. Eosinophilic gastritis affects the stomach lining, whereas eosinophilic esophagitis involves eosinophil buildup in the esophagus.

What happens if I don't treat it?

Untreated disease may lead to ulcers, scarring, strictures, and malabsorption, causing weight loss and nutritional deficiencies.

Does insurance cover care?

Coverage depends on your plan. Our team at GastroDoxs can verify benefits and handle the appropriate ICD-10 coding (K52.81) for you.

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