Crohn's Colitis

Dr. Pothuri uses a step-by-step approach:

Medical History and Physical Exam

He discusses the nature and location of your epigastric pain, reviews any weight changes, bowel habit alterations, family history of Crohn's disease, and checks for abdominal tenderness or extra-intestinal signs.

Laboratory Tests

Blood work includes a complete blood count (CBC) to detect anemia, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) for systemic inflammation, and fecal calprotectin to quantify gut-specific inflammation.

Endoscopic Evaluation

• Colonoscopy to examine the colon and terminal ileum for ulcers, strictures, and characteristic Crohn's lesions.
• Upper endoscopy if epigastric discomfort suggests involvement of the stomach or duodenum.

Imaging Studies

• MRI Enterography to visualize the small bowel, assess the extent of inflammation, and detect fistulas or abscesses.
• CT Enterography for rapid assessment in acute settings or when MRI is contraindicated.

Biopsy and Histology

Tissue samples obtained during endoscopy are examined microscopically to confirm transmural inflammation and look for granulomas typical of Crohn's disease.

Advanced Testing (if needed)

Capsule endoscopy or small-bowel follow-through studies can survey portions of the intestine beyond the reach of conventional scopes when symptoms persist.