Expert Treatment for Alpha 1 Anti Trypsin Deficiency by Dr. Bharat Pothuri
Step 1: Medical History and Exam
Dr. Pothuri reviews your family and health history. He listens to your lungs and checks for liver enlargement.
Step 2: Blood Test for A1AT Levels
A simple blood draw is done to measure A1AT (Alpha-1 Antitrypsin) protein levels.
Step 3: Genetic Testing
If low A1AT levels are detected, a DNA test confirms mutations in the SERPINA1 gene.
Step 4: Imaging and Lung Function Tests
Chest X-rays, CT scans, and spirometry assess lung damage. Liver ultrasound or FibroScan helps check for liver disease.
Frequently Asked Questions
What is the life expectancy with AATD?
It varies by individual. Early diagnosis, quitting smoking, and appropriate treatments can significantly improve long-term outcomes.
Can genetic testing detect AATD in children or newborns?
Yes. Genetic testing can identify AATD variants at any age, including newborn screening and testing in asymptomatic family members.
Can liver damage from AATD be reversed?
Mild to moderate liver injury may stabilize or improve with treatment and lifestyle changes. Advanced cirrhosis may require transplantation.
Are there clinical trials or new treatments for AATD?
Yes. Several Houston clinics and research centers are evaluating novel augmentation therapies, gene editing, and small-molecule drugs.
Will Medicare cover augmentation therapy?
Most Medicare and private plans provide at least partial coverage for A1AT augmentation infusions. Our billing team assists with benefit verification.
How should I prepare for my first visit?
Bring any prior test results (blood work, imaging), a current medication list, and details of your family history of lung or liver disease.