Collagenous colitis is a form of microscopic colitis that leads to chronic, watery diarrhea. It develops when a thin band of collagen (a natural protein) builds up just beneath the surface of the colon lining. Because the colon often looks normal during a routine scope, doctors take small tissue samples (biopsies) and examine them under a microscope to confirm the diagnosis.
Symptoms can vary but most people experience persistent digestive issues such as:
The exact cause of collagenous colitis is not fully understood, but several factors may contribute:
If collagenous colitis is impacting your daily life, don't wait to get help. At GastroDoxs in Cypress, our compassionate specialists tailor each treatment plan to your needs and offer flexible scheduling and ongoing support. Call us at 832-632-4070 or click here to book your visit online now-and take the first step toward lasting relief and better digestive health.
We've successfully treated more than 1.5K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.
With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Both are types of microscopic colitis with similar symptoms. Collagenous colitis shows a thick collagen band under the microscope, while lymphocytic colitis is characterized by an increased number of lymphocytes in the colon lining.
Diagnosis requires a colonoscopy with biopsy. Although the colon looks normal on endoscopy, tissue samples reveal the characteristic collagen layer under a microscope.
Patients typically experience chronic, watery diarrhea, often with urgency and nighttime trips to the bathroom. Other symptoms can include stomach cramps, bloating, mild weight loss, and fatigue.
Possible triggers include certain medications (like NSAIDs and antidepressants), immune system reactions, past gastrointestinal infections, and changes in gut bacteria. Genetics may play a role in some cases.
Treatment often starts with anti-diarrheal medications. Budesonide, a locally acting steroid, is commonly prescribed. Bile acid binders can help if bile salts worsen symptoms. Diet modifications, probiotics, and stress management are also important components.
Many patients benefit from reducing or avoiding caffeine, spicy foods, high-fat meals, dairy products, and artificial sweeteners. A personalized diet guide can help identify additional triggers.
Yes. In some patients, features of both collagenous and lymphocytic colitis can overlap, and treatment is tailored to the dominant findings and symptoms.
Yes. Consulting a gastroenterologist at GastroDoxs in Cypress ensures accurate diagnosis, expert-guided treatment, and close follow-up to manage symptoms effectively.
Duration varies. Some individuals experience a short-term flare that resolves, while others require ongoing treatment to control chronic symptoms.
Contact us if you have persistent or worsening diarrhea, significant abdominal pain, dehydration signs, or if over-the-counter treatments are no longer effective. Early intervention helps prevent complications.
