| Brand Name | Cosentyx |
| Generic Name | Secukinumab |
| Drug Class | Anti-Integrin Monoclonal Antibody |
| Availability | Prescription |
| Manufacturer | Novartis |
| Indications | Ulcerative Colitis, Crohn's Disease |
| Type | Injection |
| Doses | 300 mg at weeks 0, 4, 8, then every 12 weeks for maintenance |
| Route | SC Injection |
| Side Effects | Nasopharyngitis, diarrhea, headache, infections |
| Interactions | IL-17A inhibitor; may increase infection risk |
| Overdose | Severe infections, liver toxicity. |
| Missed Dose | Take ASAP or reschedule if injection missed. |
| Contraindications | Active infections, hypersensitivity, inflammatory bowel disease (IBD) caution. |
| Alternatives | Tofacitinib, Upadacitinib |
| Co-Pay Assistance Program | Not available |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Interleukin- 17 A is recommended in the management of such disorders as moderate to severe plaque psoriasis, psoriatic arthritis and ankylosing spondylitis.
Secukinumab is an interleukin-17A protein antibody which is a significant contributor to the pathogenesis of inflammatory diseases, therefore, inhibiting the inflammation and symptoms.
Most of the side effects consist of respect of upper respiratory infection, diarrhea and headache. The development of the infections or the liver changes will be the moderate to severe side effects.
Secukinumab is both in the form of the subcutaneous injection. The number of the injections can differ depending on your state and how you react to the treatment.
Secukinumab can be taken on long term but it is advisable to visit a medical practitioner frequently to monitor the possible side effects, in other words, in reference to the infections.
Secukinumab would be applied to the psoriatic arthritis and ankylosing spondylitis, but not to the rheumatoid arthritis. Talk to your doctor about other alternatives.
Secukinumab is to be used in pregnancy but inspired by the fact that the advantages of this medication will outweigh the drawbacks. It should never be taken by women who are pregnant unless the health care giver advises them to do so.
Secukinumab has been noted to be very effective in moderate to severe skin psoriasis as well as it is reported to greatly reduce the skin lesions along with the number of flare- up.
You will be supposed to make contact with your caregiver in case you lose your memory of taking one of the dosages. Should not be used twice in the same time unless the physician recommends it.
Secukinumab can be used together with the rest of the immunosuppressants and thus the medical professional should be fully aware of the drugs that a given patient is taking.
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