| Brand Name | Azulfidine |
| Generic Name | Sulfasalazine |
| Drug Class | 5-Aminosalicylate |
| Availability | Prescription |
| Manufacturer | Pfizer, Multiple generics |
| Indications | Ulcerative Colitis, Crohn's Disease |
| Type | Tablet |
| Doses | 500 mg to 1 g orally 2-4 times daily |
| Route | Oral |
| Side Effects | Nausea, rash, headache, anemia, reversible male infertility |
| Interactions | May increase bleeding with anticoagulants; avoid in sulfa allergy |
| Overdose | Nausea, headache, rash, blood disorders. |
| Missed Dose | Take ASAP. |
| Contraindications | Salicylate allergy, GI obstruction, pediatric use. |
| Alternatives | Mesalamine, Olsalazine |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Sulfasalazine is applied in the management of inflammatory bowel disorders such as ulcerative colitis and Crohn ileus and rheumatoid arthritis.
Sulfasalazine operates in a way that it suppresses the inflammation in the intestines and the joints. It is composed of anti-inflammatory substance as well as a sulfa antibiotic.
The most frequent side effects are nausea, headache, and gastrointestinal upsets. Liver, blood, or allergic reactions are the most serious side effects.
Sulfasalazine is usually administered oral in form as a tablet. Depending on the condition you are having, your doctor will prescribe you the right dosage.
No, yes, skin rashes or sensitivities can be caused by Sulfasalazine. In case it causes irritation of the skin, consult your physician.
The sulfasalazine must be administered during pregnancy when it is said to have more benefits than the risks. Ask your health care provider whether you are pregnant or you may want to become pregnant.
In case you forget to take the dose, you must take it immediately you remember unless it is nearly on the time of the next dose. Do not take two doses at once.
Yes, Sulfasalazine can also be taken in the Crohn disease and also as a component of rheumatoid arthritis treatment.
Sulfasalazine is also effective in the treatment of mild to moderate exacerbations of ulcerative colitis, it has the ability to sustain remission when taken on a regular basis.
Sulfasalazine has an ability to interact with other drugs especially those affecting the liver or kidney. Always make sure to report to your healthcare provider all the medicines you are taking.
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