| Brand Name | Asacol HD, Delzicol, Pentasa |
| Generic Name | Mesalamine |
| Drug Class | Aminosalicylate (5-ASA) |
| Availability | Prescription |
| Manufacturer | Salix Pharmaceuticals |
| Indications | Ulcerative Colitis, Crohn's Disease |
| Type | Tablet |
| Doses | 800 mg to 1.6 g orally 3-4 times daily (depends on formulation) |
| Route | Oral |
| Side Effects | Headache, abdominal pain, nausea, rare renal toxicity |
| Interactions | Minimal systemic interaction; may interact with antacids or NSAIDs |
| Overdose | Kidney problems, GI discomfort. |
| Missed Dose | Take ASAP; do not double. |
| Contraindications | Salicylate allergy, GI obstruction, blood disorders. |
| Alternatives | Sulfasalazine, Olsalazine |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Mesalamine is the drug applied to manage inflammatory bowel diseases such as ulcerative colitis through the reduction of colonic inflammation.
Mesalamine acts by suppressing the synthesis of inflammatory mediators in the bowel thereby preventing inflammation and ulceration of the colon.
The response is likely to be a headache, nausea, and abdominal pain. The side effects may be kidney trouble, and severe allergic attacks.
Mesalamine is orally delivered normally in form of a tablet or a capsule. The amount and frequency is determined by the kind of condition that is being treated and your medical practitioner guidance.
Mesalamine can in exceptional situations lead to liver problems. During treatment with this medication, your liver performance can be retailed by your healthcare provider.
Mesalamine is also viewed as a substance that should be safe during pregnancy, although you should not start taking this drug during pregnancy without consulting your healthcare provider.
When you skip a dose, take it as soon as you do not forget except in case it is nearly the time to take your next dose. Do not take two doses at once.
Yes, Mesalamine can also be used in Crohn disease as well as inflammatory bowel diseases, subject to the prescriptions of your physician.
Mesalamine can react with other drugs, particularly those which action is on kidney processes. Always make sure to tell your doctor about the other drugs that you are taking.
Mesalamine is a potent agent in induction and maintenance of remission in mild and moderate cases of ulcerative colitis to reduce the inflammation and manage an exacerbation.
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