Lymphocytic colitis is an inflammatory disorder of the large intestine in which the lining of the colon becomes irritated but without ulcers or major tissue damage. Although it may appear mild, it often causes persistent diarrhea and abdominal discomfort that can interfere with daily life. It's a relatively rare condition, affecting about 5 to 10 people per 100,000 each year, and while most cases aren't directly inherited, a family history of bowel disease may raise your risk.
Symptoms of lymphocytic colitis can vary but frequently include:
The precise cause of lymphocytic colitis is unknown, but several factors are thought to contribute:
At GastroDoxs in Katy, we combine patient-centered care and advanced digestive health expertise to diagnose and treat lymphocytic colitis effectively. Our compassionate team develops a personalized plan-using the latest diagnostics, proven medications, and lifestyle guidance-to help you find lasting relief. Ready to reclaim your quality of life? Call us or book your appointment today!
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Although not directly inherited, a family history of bowel disorders may increase your risk of developing lymphocytic colitis.
Yes; lymphocytic colitis affects about 5 to 10 people per 100,000 each year, making it less common than other forms of colitis.
The exact cause is unknown, but common triggers include certain medications (NSAIDs, antidepressants), an overactive immune response, prior gut infections, genetics, smoking, and stress.
Diagnosis requires a colonoscopy with biopsy, where tissue samples of the colon lining are examined for an increased number of lymphocytes.
Budesonide is a locally acting steroid that reduces inflammation in the colon with fewer systemic side effects compared to traditional corticosteroids.
Choose soft, low-fat foods such as white rice, cooked vegetables, and lean proteins, and avoid high-fiber, spicy, greasy, or dairy products that may worsen symptoms.
There's no guaranteed way to prevent lymphocytic colitis, but avoiding known triggers (certain medications, smoking, stress) can help reduce the risk of flare-ups.
Most patients start feeling better within four to eight weeks of beginning appropriate therapy, such as budesonide.
Yes; consulting a local gastroenterologist ensures prompt diagnosis and a personalized treatment plan tailored to your needs.
Yes; lymphocytic colitis can relapse after treatment, so ongoing monitoring and sometimes maintenance therapy may be necessary.