Abnormal liver function studies occur when blood levels of key liver enzymes and proteins fall outside their normal ranges. Tests like ALT (alanine aminotransferase), AST (aspartate aminotransferase), ALP (alkaline phosphatase) and bilirubin help your doctor evaluate liver health and detect inflammation, injury or blockage early.
The tests themselves don't cause symptoms, but the liver conditions behind abnormal results often present with:
Various factors and diseases can lead to abnormal liver enzyme or protein levels:
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With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
They indicate that your liver may be inflamed, stressed, or damaged, often due to an underlying condition affecting liver cells or function.
Not always. Mild elevations can occur from recent alcohol use, certain medications, or temporary illnesses and may resolve with lifestyle changes.
Avoid alcohol for at least 24-48 hours before testing, follow any fasting instructions, and inform your doctor about all prescription or over-the-counter medications and supplements you take.
Yes. Nonalcoholic fatty liver disease (NAFLD) commonly leads to mild elevations in ALT and AST levels as fat accumulates in liver cells.
Common codes include ICD-10-CM: R94.5 and ICD-9: 790.4, used for billing and documentation of abnormal liver enzyme findings.
If your enzyme levels remain elevated on repeat testing, or if you develop symptoms like jaundice, persistent fatigue, or abdominal pain, schedule an appointment with a gastroenterologist in Katy.
Yes. Many patients see significant improvement by adopting a balanced diet, losing excess weight, exercising regularly, and avoiding or limiting alcohol intake.
Possibly. Ultrasound, CT scan, or MRI may be ordered to assess liver structure, detect fatty changes, scarring, or other abnormalities.
It depends on the cause and treatment. Some issues resolve within weeks, while chronic conditions may take several months of therapy and lifestyle adjustment.
Not always, but in certain cases-such as unexplained chronic elevations, suspected fibrosis, or autoimmune liver disease-a biopsy may be recommended to confirm the diagnosis and guide treatment.
