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Primary Biliary Cirrhosis

At GastroDoxs in Jersey Village, we specialize in the comprehensive diagnosis and management of Primary Biliary Cirrhosis, providing advanced treatment options, supportive care, and ongoing monitoring to ensure optimal liver health and improved quality of life for our local community.

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Bharat Pothuri
Symptoms

What is Primary Biliary Cirrhosis?

Primary Biliary Cirrhosis (also called Primary Biliary Cholangitis) is a chronic liver disorder in which the small bile ducts inside the liver become inflamed and gradually destroyed. As these ducts are damaged, bile builds up and injures liver tissue over time.

Common Symptoms

PBC often has no symptoms at first. As it advances, you may notice:

  • Fatigue and feeling unusually tired
  • Itchy skin (pruritus)
  • Dry eyes or a dry mouth
  • Yellowing of the skin or eyes (jaundice)
  • Pain or discomfort in the upper right side of the abdomen
  • Dark urine and pale-colored stools

Causes

The exact cause of PBC remains unclear, but key factors include:

  • An autoimmune attack on the small bile ducts
  • Genetic predisposition or family history of PBC
  • Environmental exposures, such as certain infections or chemicals
  • Presence of anti-mitochondrial antibodies (AMA) in the bloodstream
  • Predominantly affects women between ages 30 and 60
Treatment

Treatment Options for Primary Biliary Cirrhosis in Jersey Village

Treatment includes medications, lifestyle adjustments, and monitoring:

  • Ursodeoxycholic acid (UDCA): First-line therapy to improve bile flow and normalize liver enzymes.
  • Obeticholic acid: Added for patients with an inadequate response to UDCA.
  • Pruritus relief: Cholestyramine, rifampin or antihistamines to manage itching.
  • Bone protection: Calcium and vitamin D supplements to prevent osteoporosis.
  • Balanced diet: Plenty of fruits, vegetables, lean proteins and whole grains to support liver health.
  • Low-sodium intake: Limiting salt helps reduce fluid retention.
  • Regular monitoring: Periodic blood tests (alkaline phosphatase, ALT/AST, bilirubin), imaging (ultrasound/MRI) and sometimes biopsy to track disease progression.
  • Advanced care: Referral for clinical trials or liver transplant evaluation in advanced cases.

Why Choose GastroDoxs?

With a focus on patient-centered care and comprehensive Primary Biliary Cirrhosis management, GastroDoxs in Jersey Village offers expert diagnostics, personalized treatment plans, and ongoing support to help you live well with PBC. Our compassionate team provides fast testing, clear guidance on medications and lifestyle adjustments, and regular monitoring to keep your liver health on track. Don't wait-book your appointment today and take the first step toward better liver function and long-term wellness.

1.5k

Patients Treated

We've successfully treated more than 1.5K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.

20Y

Years of Experience

With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients

Bharat Pothuri

About the Author

Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

Frequently Asked Questions

What is the ICD-10 code for Primary Biliary Cirrhosis (PBC)?

The ICD-10 code for Primary Biliary Cirrhosis, also known as Primary Biliary Cholangitis, is K74.3.

Is PBC the same as Primary Biliary Cholangitis?

Yes. PBC and Primary Biliary Cholangitis are two names for the same chronic liver disease; "cholangitis" emphasizes the inflammation of bile ducts.

How is PBC diagnosed?

PBC is diagnosed through blood tests (including anti-mitochondrial antibodies), imaging studies such as ultrasound or MRI, and sometimes a liver biopsy.

What are AMA antibodies?

AMA (anti-mitochondrial antibodies) are autoantibodies detected in most people with PBC and are a key marker used to confirm the diagnosis.

What symptoms show up first in PBC?

Early PBC often presents with fatigue and mild itching. Symptoms may be subtle initially and worsen over time.

Is PBC an autoimmune disease?

Yes. PBC is an autoimmune disorder where the body's immune system mistakenly attacks the small bile ducts in the liver.

How long can someone live with PBC?

With early detection and proper treatment, many people with PBC live a normal lifespan. Disease progression varies by individual.

What should I eat if I have PBC?

A balanced, low-salt diet rich in fruits, vegetables, lean proteins, whole grains, plus calcium and vitamin D supplements, supports liver and bone health.

How is PSC different from PBC?

Primary Sclerosing Cholangitis (PSC) affects both large and small bile ducts and is often linked to ulcerative colitis, while PBC mainly involves small ducts and primarily affects women.

How can I find a specialist near Jersey Village?

Contact the GastroDoxs team in Jersey Village for personalized gastroenterology care, fast testing, and expert management of PBC.

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