Lymphocytic Duodenitis is a mild inflammation of the duodenum, the first part of the small intestine. It occurs when more than 25 lymphocytes (a type of white blood cell) are found per 100 lining cells. These immune cells accumulate in response to various triggers and are typically identified through a biopsy during an endoscopy.
Symptoms can vary but often include:
Several factors can trigger an increase in duodenal lymphocytes:
At GastroDoxs in Jersey Village, our patient-focused team combines advanced diagnostics, board-certified expertise, and personalized treatment plans to help you conquer Lymphocytic Duodenitis. From high-accuracy biopsies to tailored diet and lifestyle guidance, we're committed to your long-term digestive health and comfort. Ready to take control of your symptoms? Book your appointment online or call us today. let's start your journey to lasting relief and wellness.
We've successfully treated more than 1.5K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.
With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Lymphocytic Duodenitis is a mild inflammation of the duodenum (first part of the small intestine) characterized by an increased number of lymphocytes (immune cells) in the intestinal lining.
Diagnosis typically involves an upper endoscopy with biopsy. A pathologist counts lymphocytes in the duodenal tissue; more than 25 per 100 epithelial cells indicates Lymphocytic Duodenitis.
In a healthy duodenum, fewer than 25 lymphocytes are found per 100 epithelial cells. Counts above this threshold suggest inflammation.
Yes. Celiac disease is a common cause. Gluten triggers an immune response that increases lymphocytes in the duodenum. A gluten-free diet often reduces inflammation.
Common symptoms include chronic diarrhea, abdominal pain or cramps, bloating, early fullness during meals, unexplained weight loss, and fatigue from poor nutrient absorption.
Besides celiac disease, it can result from food intolerances (e.g., dairy, fructose), certain medications (NSAIDs, antibiotics), gut infections, and other autoimmune disorders.
Treatment targets the underlying cause. Options include a gluten-free or elimination diet, probiotics or anti-diarrheal medications, budesonide for more severe cases, and stress reduction or low-FODMAP meal planning.
Most patients experience symptom relief within 4-8 weeks of appropriate dietary changes, medications, and lifestyle adjustments.
If you have persistent diarrhea, unexplained abdominal pain, weight loss, or fatigue, seek evaluation. Early diagnosis can prevent complications and improve quality of life.
GastroDoxs in Jersey Village offers board-certified gastroenterologists, high-accuracy biopsy testing, and comprehensive care plans-including dietary support and follow-up endoscopies-to help you heal.
