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NSAID Enteritis

NSAID enteritis is inflammation of the small intestine caused by long-term use of over-the-counter pain relievers. In Houston, Dr. Rishi Chadha offers expert diagnosis, tailored treatment, and minimally invasive procedures to alleviate symptoms, promote healing, and improve quality of life.

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Rishi Chadha

About the Expert

Dr. Rishi Chadha, MD is a board‑certified gastroenterologist who specializes in preventive gastroenterology, colorectal cancer screening, and minimally invasive endoscopic procedures. He completed his fellowship at Sunrise Health GME in Las Vegas and previously trained in internal medicine at St. Vincent’s Medical Center in Connecticut.

What Is NSAID Enteritis?

NSAID enteritis is inflammation in the small intestine caused by taking nonsteroidal anti-inflammatory drugs (NSAIDs) too often or for too long. Common NSAIDs include ibuprofen, naproxen, and aspirin. Over time, these drugs can damage the gut lining, leading to ulcers, pain, and bleeding.

Common Causes and Risk Factors

  • Frequent or high-dose NSAID use
  • Long-term NSAID therapy
  • Personal or family history of digestive issues
  • Alcohol use or smoking
  • Age over 60

Signs and Symptoms

  • Belly pain or cramping
  • Nausea or vomiting
  • Diarrhea (possibly with blood)
  • Unexplained weight loss
  • Anemia from slow, hidden bleeding

How Dr. Rishi Diagnoses NSAID Enteritis?

Dr. Rishi Chadha uses a comprehensive, step-by-step approach:

Medical History & Physical Exam

He reviews your NSAID use (type, dose, frequency), discusses symptoms like pain or bleeding, and assesses risk factors (age, alcohol, smoking, family history).

Laboratory Tests

  • Blood tests - check for anemia and markers of inflammation.
  • Stool tests - rule out infectious causes of diarrhea or bleeding.

Advanced Imaging & Endoscopy

  • Capsule endoscopy - you swallow a tiny camera pill that captures detailed images throughout the small intestine, revealing ulcers or erosions.
  • CT enterography or MRI enterography - specialized scans to visualize inflammation, ulceration, or strictures in the small bowel.

This thorough evaluation allows Dr. Chadha to pinpoint NSAID-related injury and tailor a personalized treatment plan for healing and long-term gut protection.

Dr. Rishi Chadha
Treatment

Our Houston team offers comprehensive treatment options for NSAID enteritis.

1. Lifestyle and Diet Changes

  • Stop or reduce NSAID use (under medical supervision)
  • Eat soft, small meals with lean protein and cooked vegetables
  • Add probiotics such as yogurt or kefir
  • Stay well-hydrated with plenty of water
  • Avoid alcohol

2. Medications

  • Proton pump inhibitors (PPIs) to protect and heal the gut lining
  • Misoprostol to increase protective mucus in the intestine
  • Iron supplements to treat anemia from chronic bleeding
  • Biologic or immunomodulator drugs for more severe inflammation

3. Minimally Invasive Procedures

  • Balloon dilation to widen narrowed segments of the small intestine
  • Capsule or push enteroscopy to locate and treat small lesions
  • Endoscopic hemostasis to safely stop bleeding without surgery
Rishi Chadha

About the Author

Dr. Rishi Chadha, MD is a board‑certified gastroenterologist who specializes in preventive gastroenterology, colorectal cancer screening, and minimally invasive endoscopic procedures. He completed his fellowship at Sunrise Health GME in Las Vegas and previously trained in internal medicine at St. Vincent’s Medical Center in Connecticut.

Frequently Asked Questions

What is NSAID enteritis?

It's inflammation (swelling) in the small intestine caused by overuse or long-term use of NSAIDs.

Are NSAIDs enteric drugs?

No. Enteric-coated drugs are designed to protect the gut. Standard NSAIDs like ibuprofen, naproxen, and aspirin can harm the intestinal lining over time.

How is NSAID enteritis diagnosed?

Dr. Chadha reviews your symptoms and NSAID history, performs a physical exam, and may order lab tests, stool studies, imaging, or a small-camera procedure.

What tests are used?

Common tests include blood work (for anemia and inflammation), stool tests (to rule out infection), capsule endoscopy, and CT or MRI enterography.

How is it treated?

Treatment involves stopping or reducing NSAIDs under medical guidance, taking gut-healing medications (like PPIs or misoprostol), following a gentle diet, and using endoscopic therapies if needed.

What foods help healing?

Soft, small meals with lean protein and cooked vegetables, plus probiotics such as yogurt or kefir, can support gut recovery.

How long does recovery take?

Mild cases may improve in a few weeks; more severe inflammation or ulcers can take several months to heal fully.

Can this become Crohn's disease?

No. NSAID enteritis is drug-related damage, whereas Crohn's is an autoimmune condition. Dr. Chadha will explain the differences during diagnosis.

When should I see a specialist?

Make an appointment if you experience persistent belly pain, gastrointestinal bleeding, unexplained weight loss, or anemia symptoms.

Are non-surgical options available?

Yes. Dr. Chadha offers minimally invasive endoscopic treatments'like balloon dilation or endoscopic hemostasis-to manage most cases without surgery.

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