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Indeterminate Colitis

Indeterminate colitis is an inflammatory bowel disease blending features of ulcerative colitis and Crohn's disease, often diagnosed when symptoms overlap. In Houston, Dr. Nghia Nguyen at GastroDoxs specializes in identifying, treating, and managing this condition through care and advanced therapies.

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Nghia Nguyen

About the Expert

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Common Causes and Risk Factors

  • Family history of inflammatory bowel disease
  • Aberrant immune response that injures the intestinal lining
  • Environmental triggers such as stress or smoking
  • Most often diagnosed between ages 15 and 35

Signs and Symptoms

  • Abdominal pain or cramping
  • Frequent, urgent trips to the bathroom
  • Diarrhea, sometimes with blood
  • Fatigue or unexplained weight loss
  • Fever or dehydration during flare-ups

How Dr. Nghia Nguyen Diagnoses Epigastric Pain in Indeterminate Colitis

Dr. Nguyen uses a step-by-step approach:

Medical History and Physical Exam

He reviews your epigastric pain characteristics, bowel habits, weight changes, family history of IBD, and any dietary or stress‐related triggers.

Blood and Stool Tests

He orders a complete blood count (CBC), C‐reactive protein (CRP), and erythrocyte sedimentation rate (ESR) to assess inflammation and anemia. Stool studies rule out infections.

Imaging Studies

  • CT or MR enterography to detect bowel wall thickening, strictures, or other structural changes.
  • Abdominal ultrasound for a quick, noninvasive look at bowel loops and fluid collections.

Endoscopy and Biopsy

He performs a colonoscopy to visualize the colon and terminal ileum, taking targeted biopsies. Pathology helps distinguish indeterminate colitis from ulcerative colitis or Crohn's disease.

Dr. Nghia Nguyen
Treatment

Our Team offers a full range of care for indeterminate colitis.

1. Lifestyle and Diet Tips

  • Eat soft, low-fiber foods during flares
  • Drink plenty of water to stay hydrated
  • Avoid trigger foods that upset your stomach
  • Incorporate stress-reducing activities like yoga or meditation
  • Keep a food journal to track symptom patterns

2. Medications

  • Anti-inflammatory drugs to reduce gut inflammation
  • Steroids for rapid control of acute flare-ups
  • Immune-modifying therapies to regulate immune response
  • Biologic agents that block specific inflammation pathways

3. Minimally Invasive or Advanced Procedures

  • Endoscopic treatments to dilate or treat narrowed bowel segments
  • Laparoscopic surgery to remove severely damaged portions of intestine
  • Ongoing monitoring with imaging and endoscopy for disease tracking
Dr Nghia Nguyen

About the Author

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Frequently Asked Questions

How is indeterminate colitis different from Crohn's or ulcerative colitis?

Indeterminate colitis shows features of both diseases but doesn't fit neatly into either category. Over time, additional tests and observation may clarify the exact diagnosis.

Can food changes alone manage indeterminate colitis?

Dietary adjustments can ease symptoms but most patients require medication to control inflammation and prevent flares.

Will I need surgery for indeterminate colitis?

Surgery is only recommended if medications and less invasive procedures fail or if complications such as strictures or perforations occur.

What kind of follow-up care will I need?

You'll have regular office visits, blood and stool tests, and sometimes repeat colonoscopies to monitor disease activity and treatment response.

Are support groups available in Houston?

Yes. The Crohn's & Colitis Foundation offers local chapters, support meetings, and online forums for patients and families.

Is it safe to travel with indeterminate colitis?

Travel is generally safe if you follow your treatment plan, pack your medications, stay hydrated, and know where to find medical care if needed.

How soon will I start feeling better?

Many people notice symptom relief within a few weeks of starting treatment, but timelines vary based on individual severity and therapy chosen.

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