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Crohn's Esophagitis

Crohn's esophagitis is a rare form of Crohn's disease that inflames the esophagus, causing painful swallowing, chest discomfort and potential complications. At GastroDoxs in Houston, Dr. Nghia Nguyen offers diagnosis, personalized treatment plans and advanced endoscopic therapies to restore health.

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Nghia Nguyen

About the Expert

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

What Is Crohn's Esophagitis?

Crohn's esophagitis is a rare form of Crohn's disease in which the lining of the esophagus becomes inflamed. This inflammation can make swallowing painful, cause chest discomfort, and lead to other complications if left untreated.

Common Causes and Risk Factors

  • Autoimmune dysfunction - the immune system attacks healthy esophageal tissue
  • Genetic predisposition - a family history of Crohn's disease
  • Smoking - can worsen esophageal inflammation
  • Stress, poor diet, and certain medications that may trigger flares

Signs and Symptoms

  • Pain or burning sensation when swallowing (odynophagia)
  • Sensation of food getting stuck in the throat (dysphagia)
  • Chest pain or persistent heartburn
  • Nausea or vomiting after meals
  • Unintentional weight loss and decreased appetite

How Dr. Nghia Nguyen Diagnoses Crohn's Esophagitis?

Dr. Nguyen uses a step-by-step approach:

Symptom Assessment and Medical History

He reviews your epigastric pain, difficulty swallowing, weight changes and family history of Crohn's or autoimmune disease.

Upper Endoscopy

An endoscope is passed into your esophagus to look for inflammation, ulcers or strictures.

Biopsy

Small tissue samples are taken during endoscopy to confirm Crohn's-related inflammation and exclude infections or other causes.

Imaging Studies

  • Esophagram (barium swallow) evaluates swallowing mechanics and detects narrowing.
  • CT or MR enterography checks for inflammation elsewhere in the GI tract.

Additional Tests (if needed)

Blood work measures inflammatory markers, checks for anemia and rules out other conditions mimicking Crohn's esophagitis.

Dr. Nghia Nguyen
Treatment

Our Team offers a full range of care for Crohn's esophagitis.

1. Lifestyle and Diet Modifications

  • Eat soft, small meals to reduce esophageal irritation
  • Stay well-hydrated to ease swallowing
  • Avoid spicy, acidic, or very hot foods
  • Quit smoking to lower inflammation
  • Manage stress with gentle exercise or relaxation techniques

2. Medications

  • Proton pump inhibitors (PPIs) to reduce stomach acid
  • Steroids for short-term inflammation control
  • Biologics or immune-modulating drugs for long-term disease management
  • Pain relief options as needed to ease discomfort

3. Minimally Invasive or Advanced Procedures

  • Endoscopic dilation to widen narrowed areas of the esophagus
  • Stent placement to hold open strictured segments
  • Intralesional injections to target localized inflammation
Dr Nghia Nguyen

About the Author

Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.

Frequently Asked Questions

How is Crohn's esophagitis different from GERD?

Crohn's esophagitis results from immune‐mediated inflammation of the esophageal lining, whereas GERD is caused by stomach acid reflux. An upper endoscopy with biopsy can distinguish between the two.

What causes Crohn's esophagitis?

It develops when an overactive immune system attacks the esophagus. Genetics, smoking, stress, poor diet, and certain medications can increase your risk.

How is Crohn's esophagitis treated?

Treatment typically combines a gentle diet, medications (like PPIs, steroids, biologics), and, if needed, endoscopic procedures such as dilation or stent placement.

How fast will I feel better?

Many patients notice symptom relief within a few weeks of starting therapy. Achieving long-term control may take several months and ongoing follow-up.

Can I treat it with diet only?

A soft, low‐irritant diet can ease swallowing, but most people also require medications or procedures to fully manage inflammation.

Is endoscopic dilation safe?

Yes. In experienced hands, dilation has a low risk of bleeding or small tears. Dr. Nguyen uses advanced techniques to minimize complications.

When should I see a GI specialist?

If you have persistent pain when swallowing, chest discomfort, or unexplained weight loss, schedule an evaluation promptly. Early diagnosis leads to better outcomes.

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