What Is Pancreatic Cancer?
Pancreatic cancer occurs when abnormal cells form in the tissues of the pancreas, the organ behind your stomach that helps with digestion and blood sugar regulation. If not detected early, these cells can invade nearby structures or spread (metastasize) to other organs. Early diagnosis offers the best chance for effective treatment.
Common Causes and Risk Factors
- Smoking or long-term tobacco use
- Heavy alcohol consumption
- Chronic pancreatitis (long-standing pancreatic inflammation)
- Family history of pancreatic or other cancers
- Obesity and diets high in fat
- Age over 60
Signs and Symptoms
- Jaundice (yellowing of the skin and eyes)
- Unexplained weight loss
- Pain in the upper abdomen or back
- Loss of appetite
- New-onset diabetes or worsening blood sugar control
Expert Treatment for Pancreatic Cancer by Dr. Bharat Pothuri
Dr. Pothuri uses a step-by-step approach:
Medical History and Physical Exam
He reviews your pattern of epigastric pain, changes in appetite or weight, personal and family history of GI cancers, alcohol and tobacco use, and performs a focused abdominal exam.
Blood Tests
We measure CA 19-9 (a pancreatic tumor marker), liver function tests, bilirubin levels, and pancreatic enzymes (amylase and lipase) to assess for inflammation or obstruction.
Imaging Studies
- Contrast-enhanced CT scan of the abdomen to detect pancreatic masses, ductal dilation, and local spread.
- MRI/MRCP for high-resolution images of the pancreatic ducts and surrounding soft tissues.
- Endoscopic ultrasound (EUS) for detailed visualization of the pancreas and adjacent structures.
Endoscopic Evaluation and Biopsy
If imaging raises suspicion, EUS-guided fine-needle aspiration is performed to obtain tissue and confirm the diagnosis, tumor type, and stage.
Frequently Asked Questions
What are the first symptoms of pancreatic cancer?
Early signs may include yellowing of the skin or eyes (jaundice), unexplained weight loss, upper abdominal or back pain, loss of appetite, and new-onset diabetes. Always check with your doctor if you notice these changes.
What causes pancreatic cancer?
The exact cause is unknown, but risk factors include smoking, heavy alcohol use, chronic pancreatitis, a family history of pancreatic or other cancers, obesity, and age over 60.
Is pancreatic cancer curable?
If caught in an early stage, surgery to remove the tumor may be curative. In later stages, treatments aim to control the disease, relieve symptoms, and improve quality of life.
How is stage 4 pancreatic cancer treated?
Treatment usually includes chemotherapy, targeted therapies when specific tumor markers are present, pain management, and supportive care to slow progression and manage symptoms.
How soon should I see a specialist in Houston?
Schedule an appointment as soon as you experience any warning signs. Early evaluation by a specialist like Dr. Pothuri offers the best range of treatment options.
Do you offer second opinions?
Yes. Dr. Pothuri welcomes second-opinion requests and can review your scans, pathology, and treatment history to help you make informed decisions.
What support services are available?
Our team provides nutrition counseling, pain and symptom management, emotional support, and access to clinical trials-all coordinated here in Houston to support you every step of the way.