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Lymphocytic Duodenitis

Dr. Bharat Pothuri at GastroDoxs in Houston offers expert evaluation and treatment for lymphocytic duodenitis, an inflammation of the duodenum caused by immune reactions or food sensitivities. Through personalized dietary guidance, advanced diagnostics, and targeted therapies, patients achieve lasting relief.

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Bharat Pothuri

About the Expert

Dr. Bharat Pothuri is a board-certified gastroenterologist and the founder of GastroDoxs. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

What Is Lymphocytic Duodenitis?

Lymphocytic duodenitis is inflammation of the duodenum (the first part of the small intestine) caused by an excessive buildup of lymphocytes (a type of white blood cell) in its lining. It often leads to abdominal discomfort, bloating, and digestive issues after meals.

Common Causes and Risk Factors

  • Celiac disease or other autoimmune disorders
  • Food sensitivities (gluten, dairy, etc.)
  • Bacterial or viral gastrointestinal infections
  • Use of NSAIDs and certain other medications
  • Family history of gut-related conditions

Signs and Symptoms

  • Abdominal pain or cramps, especially after eating
  • Bloating and excessive gas
  • Nausea or occasional mild vomiting
  • Unintended weight loss
  • Fatigue, weakness, or iron-deficiency anemia

Expert Treatment for Lymphocytic Duodenitis by Dr. Bharat Pothuri

Dr. Pothuri uses a step-by-step approach:

Medical History and Physical Exam

He discusses your epigastric pain, eating habits, family history of gut disorders, and other risk factors.

Blood Tests

We screen for celiac disease antibodies, check nutrient levels (iron, B12), and rule out other immune-mediated causes.

Endoscopic Evaluation

An upper endoscopy allows direct visualization of the duodenum and collection of small biopsies to quantify lymphocyte infiltration.

Breath Tests

  • Hydrogen breath test to assess for small intestinal bacterial overgrowth (SIBO).
  • Lactose or fructose breath tests to identify carbohydrate malabsorption.
Dr. Bharat Pothuri
Treatment

Our Team offers a full range of care for lymphocytic duodenitis.

1. Diet and Lifestyle Changes

  • Try a gluten-free or low-FODMAP diet if needed
  • Eat small meals more often to ease digestion
  • Avoid alcohol, caffeine, and spicy foods that can irritate
  • Work with our dietitian for tailored meal planning

2. Medications

  • Acid blockers to calm stomach acid production
  • Anti-inflammatory drugs to reduce intestinal swelling
  • Probiotics to restore healthy gut flora
  • Iron or B12 supplements if blood levels are low

3. Advanced Procedures

  • Endoscopic balloon dilation to relieve strictures
  • Capsule endoscopy for detailed small-intestine imaging
  • Biologic therapies for immune-mediated cases
306

Patients Treated

Dr. Pothuri has treated more than 306 patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.

20Y

Years of Experience

With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients

Bharat Pothuri

About the Author

Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

Frequently Asked Questions

What is lymphocytic duodenitis?

It's inflammation of the duodenum marked by excess lymphocytes in the lining, causing pain, bloating, and malabsorption.

How is it diagnosed?

Diagnosis uses endoscopy with biopsy showing increased intraepithelial lymphocytes, plus blood tests to exclude celiac disease.

What causes lymphocytic duodenitis?

Causes include celiac spectrum, NSAIDs, food sensitivities, infections, and autoimmune conditions.

How is it treated?

Treatment involves dietary changes (gluten?free or low?FODMAP), acid suppression, and nutritional supplementation.

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