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Eosinophilic Colitis

Eosinophilic colitis is a rare inflammatory condition of the large intestine caused by excessive eosinophils. Symptoms include abdominal pain, diarrhea, and weight loss. At GastroDoxs in Houston, Dr. Pothuri offers comprehensive diagnosis and personalized treatment plans for effective lasting relief.

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Bharat Pothuri

About the Expert

Dr. Bharat Pothuri is a board-certified gastroenterologist and the founder of GastroDoxs. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

What Is Eosinophilic Colitis?

Eosinophilic colitis is a rare inflammatory disorder of the large intestine marked by an abnormal buildup of eosinophils (a type of white blood cell). This overgrowth can cause abdominal pain, diarrhea, and other gastrointestinal symptoms.

Common Causes and Risk Factors

  • Food sensitivities -Certain foods may trigger an immune response in the colon.
  • Allergies -A history of allergic conditions can increase the risk.
  • Family history -Genetic factors may play a role in susceptibility.
  • Other GI disorders -Coexisting gastrointestinal conditions can contribute.

Signs and Symptoms

  • Abdominal pain or cramping
  • Persistent diarrhea
  • Unintended weight loss
  • Loss of appetite
  • Blood or mucus in the stool
  • Fatigue or weakness

Expert Treatment for Eosinophilic Colitis by Dr. Bharat Pothuri

Dr. Pothuri uses a step-by-step approach:

Medical History and Exam

He reviews your symptoms, dietary habits, allergy history, and any family history of gastrointestinal disorders.

Blood Tests

A complete blood count checks for elevated eosinophils and helps rule out other causes of inflammation.

Stool Tests

Stool studies exclude infections, parasites, and other inflammatory conditions.

Colonoscopy with Biopsy

A colonoscopy allows direct visualization of the colon lining. Small tissue samples (biopsies) confirm the presence and extent of eosinophil buildup.

Imaging Studies

  • Abdominal ultrasound or CT scan can detect colon wall thickening or other structural changes.
  • Magnetic resonance enterography (MRE) provides detailed images of the bowel if needed.

Allergy and Dietary Testing

Food allergy panels and an elimination diet help pinpoint specific dietary triggers that may be driving the eosinophilic response.

Dr. Bharat Pothuri
Treatment

Our Team offers a full range of care for eosinophilic colitis.

1. Lifestyle and Diet Modifications

  • Elimination diet to remove potential trigger foods
  • Food allergy testing to pinpoint sensitivities
  • Nutrition support from a dietitian to maintain strength and health

2. Medications

  • Steroids to reduce inflammation and eosinophil counts
  • Leukotriene blockers to calm immune responses
  • Biologics to target and stop chronic inflammation

3. Minimally Invasive or Advanced Procedures

  • Endoscopic therapy to treat strictures or narrowing in the colon
  • Surgical intervention for severe or refractory cases
1K

Patients Treated

Dr. Pothuri has treated more than 1K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.

20Y

Years of Experience

With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients

Bharat Pothuri

About the Author

Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

Frequently Asked Questions

What is eosinophilic esophagitis (EoE)?

EoE is an allergic condition where white blood cells (eosinophils) build up in the esophagus, causing inflammation and swallowing difficulties.

What triggers eosinophilic esophagitis?

Common triggers include food allergens (milk, wheat, eggs, nuts), environmental allergens (pollen), and acid reflux.

How is EoE diagnosed?

Diagnosis requires upper endoscopy with biopsy. Pathology shows elevated eosinophil counts in the esophageal lining.

What are the main symptoms?

Symptoms include trouble swallowing, food impaction (food getting stuck), chest pain, and persistent heartburn.

How is EoE treated?

Treatment often combines dietary elimination of triggers, topical steroids (swallowed inhalers), and esophageal dilation for strictures.

Can diet alone manage EoE?

Many patients benefit from a six-food elimination diet (removing dairy, wheat, soy, eggs, nuts, seafood) followed by staged reintroduction.

Is EoE a lifelong condition?

Yes. EoE is chronic. Ongoing management with diet, medication, and periodic endoscopies helps control inflammation and prevent complications.

When should I see a gastroenterologist?

Consult a specialist if you experience frequent swallowing problems, food impaction, or persistent chest discomfort not relieved by antacids.

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