1.9K Reviews    |    4.7 Star Rating    |    20+ years of experience    |    72k+ Patients Treated

Ampullary Adenomacarcinoma

Discover specialized care for ampullary adenocarcinoma in Houston with Dr. Bharat Pothuri at GastroDoxs. As a gastroenterologist, he offers personalized treatment plans-from diagnosis using advanced imaging and endoscopic techniques to minimally invasive procedures and surgical management, ensuring compassionate expertise.

Call Us 832-632-4070 Schedule Now Click Here Text Us 832-632-4070 Learn More Click Here
Texas Medical Board
Harris County Medical Society
American College of Gastroenterology
American Society for Gastrointestinal Endoscopy
Memorial hermann
Houston Methodist leading Medicine
HCA Houston Healthcare
Bharat Pothuri

About the Expert

Dr. Bharat Pothuri is a board-certified gastroenterologist and the founder of GastroDoxs. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

What Is Ampullary Adenocarcinoma?

Ampullary adenocarcinoma is a rare cancer that arises at the ampulla of Vater-the junction where the bile duct and pancreatic duct meet. Tumors in this location can block the flow of bile and digestive juices, leading to jaundice and other complications.

Common Causes and Risk Factors

  • Age over 60
  • Family history of colon polyps or stomach cancer
  • Chronic pancreatitis or gallstones
  • Smoking or heavy alcohol use
  • Inherited syndromes (for example, Lynch syndrome)

Signs and Symptoms

  • Yellowing of the skin or eyes (jaundice)
  • Dark urine and pale, clay-colored stools
  • Itchy skin
  • Upper abdominal pain or discomfort
  • Nausea, vomiting, or unexplained weight loss

Expert Treatment for Ampullary Adenomacarcinoma by Dr. Bharat Pothuri

Dr. Pothuri uses a step-by-step approach:

Medical History and Exam

He reviews your symptoms-especially epigastric pain, jaundice, weight loss-and checks for risk factors such as family history of GI cancers, smoking, or chronic pancreatitis.

Blood Tests

Laboratory studies include liver function tests (AST, ALT, alkaline phosphatase, bilirubin) and tumor markers (CA 19-9) to assess bile duct obstruction and cancer suspicion.

Cross-Sectional Imaging

  • Contrast-enhanced CT scan evaluates the ampulla, pancreas, and regional lymph nodes.
  • MRCP (Magnetic Resonance Cholangiopancreatography) noninvasively visualizes the biliary and pancreatic ducts for strictures or masses.

Endoscopic Evaluation

  • Endoscopic Ultrasound (EUS) provides high-resolution imaging of the ampulla and allows fine-needle aspiration of suspicious lesions.
  • ERCP (Endoscopic Retrograde Cholangiopancreatography) confirms ductal obstructions, enables targeted biopsies, and can place stents to relieve jaundice.

Pathology and Multidisciplinary Review

Biopsy specimens are examined by GI pathologists. Findings are discussed in a multidisciplinary tumor board to finalize staging and tailor your treatment plan.

Dr. Bharat Pothuri
Treatment

Our Houston team provides comprehensive treatment options for ampullary adenocarcinoma.

1. Lifestyle and Diet Adjustments

  • Eat small, low-fat meals to ease digestion and reduce biliary stress
  • Avoid smoking and alcohol to help slow disease progression
  • Stay well-hydrated and choose plenty of fruits, vegetables, and lean proteins

2. Medication Therapies

  • Personalized chemotherapy regimens to target cancer cells
  • Targeted drugs for tumors with specific molecular markers
  • Supportive medications to manage nausea, itching, and other side effects

3. Minimally Invasive and Surgical Interventions

  • ERCP with stent placement to relieve bile duct obstructions
  • Laparoscopic or robotic-assisted surgery for precise biopsies or tumor removal
  • Whipple procedure for curative resection in eligible patients
1K

Patients Treated

Dr. Pothuri has treated more than 1K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.

20Y

Years of Experience

With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients

Bharat Pothuri

About the Author

Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

Frequently Asked Questions

What is ampullary adenocarcinoma?

Ampullary adenocarcinoma is a rare cancer that starts where the bile duct and pancreatic duct meet, called the ampulla of Vater.

What symptoms should I look for?

Common signs include jaundice (yellowing of skin or eyes), dark urine, pale or clay-colored stools, itchy skin, upper abdominal pain, nausea, vomiting, and unexplained weight loss.

How is ampullary adenocarcinoma diagnosed?

Diagnosis typically involves blood tests, imaging (CT scan or MRCP), endoscopic ultrasound (EUS) with biopsy, and ERCP to visualize and sample the tumor.

What treatment options are available?

Treatment may include lifestyle and dietary changes, chemotherapy, targeted drugs, endoscopic stenting, minimally invasive or robotic surgery, and, if needed, Whipple surgery to remove the tumor.

Is surgery always required?

Not always. Some patients benefit from non-surgical methods like stenting or chemotherapy alone, depending on tumor stage and overall health.

Can diet and lifestyle help during treatment?

Yes. A low-fat diet, small frequent meals, good hydration, smoking cessation, and limiting alcohol can support digestion and overall well-being.

When should I see a specialist?

If you experience jaundice, persistent abdominal pain, unexplained weight loss, or other warning signs, schedule an evaluation with Dr. Pothuri promptly.

Related Blogs
Abdominal Pain

What Are The Treatment Options for My Loved One with Colon Cancer?

Read More
Abdominal Pain

Dysphagia

Read More
Abdominal Pain

The Difference Between a Bellyache and Abdominal Pain

Read More