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Abnormal Liver Function Studies (Lfts)

Abnormal liver function tests (LFTs) indicate liver stress or dysfunction. At GastroDoxs Houston, Dr. Bharat Pothuri employs comprehensive evaluations-medical history, physical exams, imaging-to diagnose conditions like fatty liver, hepatitis, or drug-induced injury and craft personalized treatment plans optimizing liver health.

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Bharat Pothuri

About the Expert

Dr. Bharat Pothuri is a board-certified gastroenterologist and the founder of GastroDoxs. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

What Are Abnormal Liver Function Studies (LFTs)?

Liver function tests measure key enzymes and proteins in your blood. Results outside the normal range-called -abnormal LFTs--suggest your liver may be under stress or not working properly. Early detection allows for timely evaluation and treatment.

Common Causes and Risk Factors

  • Nonalcoholic fatty liver disease (NAFLD)
  • Heavy alcohol use
  • Viral hepatitis A, B, or C
  • Side effects of certain medications (e.g., statins, antibiotics)
  • Autoimmune liver disorders
  • Obesity or overweight
  • Type 2 diabetes and insulin resistance
  • High cholesterol or triglycerides
  • Family history of liver disease
  • Long-term use of prescription drugs

Signs and Symptoms

  • Often none in early stages
  • Fatigue or general weakness
  • Jaundice (yellowing of skin or eyes)
  • Dark urine or pale stools
  • Mild pain or fullness in the upper right abdomen
  • Unexplained weight loss
  • Itchy skin
  • Swelling in legs or abdomen (advanced disease)

Expert Treatment for Abnormal Liver Function Studies (Lfts) by Dr. Bharat Pothuri

Dr. Pothuri uses a step-by-step approach:

Medical History and Exam

He reviews your full health history, including alcohol intake, medication use, metabolic risk factors (diabetes, obesity), and any family history of liver disease. A focused abdominal exam looks for signs of liver enlargement or fluid buildup.

Blood Tests

We draw a comprehensive LFT panel (ALT, AST, ALP, GGT, bilirubin, albumin) and may add viral hepatitis serologies (A, B, C), autoimmune markers, and iron studies to pinpoint the cause of enzyme elevation.

Imaging Studies

  • Abdominal ultrasound assesses liver size, texture, and fat infiltration.
  • FibroScan (transient elastography) measures liver stiffness to screen for fibrosis.
  • Cross-sectional imaging (CT or MRI) if focal lesions or advanced disease are suspected.

Advanced Testing (if needed)

When noninvasive tests are inconclusive, a percutaneous liver biopsy may be performed to confirm diagnosis, assess fibrosis stage, or guide targeted therapy.

Bharat Pothuri
Treatment

Our Team offers a full range of care for fatty liver disease.

1. Lifestyle and Diet Modifications

  • Customized meal plans rich in fruits, vegetables, and lean proteins
  • Guidance on limiting or avoiding alcohol
  • Weight-loss goals (5-10% of body weight) to reduce liver fat
  • Structured exercise programs to lower liver enzymes and improve health

2. Medications

  • Antiviral therapies for hepatitis B and C
  • Immunosuppressive regimens for autoimmune hepatitis
  • Vitamin D and other supplements if levels are low
  • Cholesterol- and blood sugar-lowering medications as needed

3. Minimally Invasive or Advanced Procedures

  • FibroScan for non-surgical monitoring of liver stiffness
  • Endoscopic treatments (e.g., ERCP) for bile duct blockages
  • Paracentesis to remove ascitic fluid
  • Transjugular intrahepatic portosystemic shunt (TIPS) for advanced cirrhosis
5.2K

Patients Treated

Dr. Pothuri has treated more than 5.2K patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.

20Y

Years of Experience

With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients

Bharat Pothuri

About the Author

Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

Frequently Asked Questions

What are liver function tests (LFTs)?

These are blood tests that check how well your liver is working by measuring liver enzymes, proteins, and bilirubin.

What causes abnormal liver function tests?

Common causes include fatty liver, hepatitis, alcohol use, medications, autoimmune conditions, or bile duct issues.

Can I have abnormal LFTs without symptoms?

Yes. Many people have no symptoms. Abnormal LFTs are often discovered during routine blood work or screening.

Do I need to fast before a liver function test?

Fasting is not usually needed, but your doctor may ask you to fast if other tests are ordered with it.

How are abnormal LFTs treated?

Treatment depends on the cause. It may involve stopping certain medications, lifestyle changes, or further testing.

Can liver enzyme levels return to normal?

Yes. With the right care and by treating the underlying issue, liver enzymes often return to normal ranges.

What follow-up tests might I need?

You may need imaging tests like ultrasound or FibroScan, hepatitis panels, or additional blood work.

Should I worry if only one liver enzyme is slightly elevated?

A single mild elevation may not be serious. Your provider will track trends over time to decide if further action is needed.

When should I see a liver specialist?

If liver tests remain abnormal or symptoms develop, it's a good idea to consult a gastroenterologist or hepatologist.

Can medications affect my LFT results?

Yes. Some medications, including over-the-counter pain relievers and supplements, can impact liver enzymes.

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