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Granuloma in Intestine

Our service offers precise diagnosis and targeted treatment guidance for intestinal granulomas, ensuring each patient receives personalized, effective care for long-term digestive wellness.

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Harris County Medical Society
American College of Gastroenterology
American Society for Gastrointestinal Endoscopy
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Houston Methodist leading Medicine
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Bharat Pothuri
Symptoms

What Is a Granuloma in the Intestine?

A granuloma is a small cluster of immune cells that forms when your body tries to wall off an infection or irritant in the gut. It's an inflammatory reaction, not a tumor, and often shows up on imaging or during an intestinal biopsy.

Common Symptoms

Many people don't notice a granuloma until it causes problems. Signs to watch for include:

  • Abdominal cramps or persistent belly pain
  • Chronic diarrhea or loose stools
  • Unexplained weight loss
  • Low-grade fever or night sweats
  • Occasional blood in the stool

Causes

Granulomas form when the immune system responds to certain triggers in the intestine:

  • Infections such as tuberculosis or Yersinia
  • Inflammatory bowel disease, especially Crohn's disease
  • Autoimmune conditions like sarcoidosis
  • Reaction to swallowed foreign material or irritants
Treatment

Treatment Options for Intestinal Granulomas in Cypress

Treatment includes medication, diet modifications, and procedural care:

  • Anti?inflammatory medications: Steroids or 5-ASA agents to reduce gut inflammation.
  • Immune modulators and biologics: Drugs like azathioprine or TNF inhibitors to calm an overactive immune response.
  • Antibiotics: Prescribed when an underlying infection (e.g., TB or bacterial overgrowth) is identified.
  • Diet and nutrition: Soft, low-fiber meals during flare-ups and tailored nutrition plans to prevent weight loss.
  • Supplement support: Vitamins (B12, D) and iron or calcium supplements to correct deficiencies.
  • Procedural follow-up: Periodic colonoscopy or endoscopy with biopsy to monitor granuloma resolution.
  • Surgical intervention: Reserved for complications such as strictures, fistulas, or nonresponsive disease.
  • Ongoing monitoring: Regular blood tests (CRP, ESR) and imaging (CT/MRI) to track disease activity.

Why Choose GastroDoxs in Cypress?

At GastroDoxs, your digestive health is our top priority. Our board-certified gastroenterologists combine advanced diagnostics, in-office procedures, and personalized treatment plans to address intestinal granulomas and related GI conditions. You'll receive compassionate, patient-centered care every step of the way-from accurate diagnosis to long-term management. Don't wait to feel better: book your appointment today and let us help you regain comfort and confidence in your digestive health.

Patients Treated

We've successfully treated more than 342 patients, helping individuals improve their digestive health and overall well-being through expert, personalized care.

20Y

Years of Experience

With over 20 years of experience, GastroDoxs has been a trusted provider of gastroenterology care, focusing on delivering the best outcomes for patients

Bharat Pothuri

About the Author

Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.

Frequently Asked Questions

What does it mean if a granuloma is found during colonoscopy?

Finding a granuloma during colonoscopy indicates a localized area of inflammation or immune activity in the intestine. Further tests-such as biopsies, blood work, or imaging-are needed to determine the exact cause.

What conditions cause these lumps?

Granulomas can form due to Crohn's disease, long-term infections (e.g., tuberculosis), foreign-body reactions (like sutures), or in some cases idiopathic (unknown) reasons.

Can granulomas lead to weight loss?

Yes. Chronic inflammation in the gut can interfere with nutrient absorption and appetite, often resulting in unintended weight loss over time.

Is this a serious condition?

It varies. Some granulomas are mild and resolve with medication, while others may signal a chronic disease like Crohn's, requiring ongoing management.

How is it diagnosed?

Diagnosis typically involves colonoscopy with biopsy, imaging studies (CT or MRI), and laboratory tests such as blood counts, inflammatory markers, or stool analyses.

How long does it take to recover after removal?

Recovery time depends on the treatment but most patients feel better within 1-2 weeks following medication adjustments, dietary changes, or minimally invasive procedures.

Can it be treated without surgery?

Yes. Many patients respond well to anti-inflammatory medications, immune-modulating therapies, antibiotics (if infection is present), and dietary modifications without needing surgery.

When should I see a specialist?

You should consult a gastroenterologist if you experience persistent abdominal pain, ongoing diarrhea, unexplained weight loss, fever, or any new changes in bowel habits.

Can diet help?

Absolutely. A tailored diet-often low in fiber and easy to digest-along with nutritional supplements can reduce symptoms, support healing, and improve overall gut health.

Is it passed down in families?

Granulomas themselves are not directly inherited, but a family history of inflammatory bowel disease (IBD) like Crohn's can increase your risk of developing similar intestinal conditions.

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