| Brand Name | Zofran |
| Generic Name | Ondansetron |
| Drug Class | Dopamine (D2) Antagonist |
| Availability | Prescription |
| Manufacturer | GlaxoSmithKline |
| Indications | Nausea, Vomiting |
| Type | Tablet, Oral Solution, Injection |
| Doses | 4-8 mg every 8 hours |
| Route | Oral, IV |
| Side Effects | Headache, constipation, dizziness, QT prolongation |
| Interactions | May prolong QT interval; interacts with serotonergic drugs |
| Overdose | Irregular heartbeat, dizziness, headache. |
| Missed Dose | Take ASAP; skip if near next. |
| Contraindications | Hypersensitivity to ondansetron, apomorphine use, congenital QT syndrome. |
| Alternatives | Granisetron, Palonosetron, Dolasetron |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Ondasetron is employed in preventing nausea and vomiting as a result of chemotherapy, radiation therapy and surgery.
The mechanism of Ondansetron is to block serotonin receptors in the brain and gastrointestinal tract which cause nausea and vomiting.
Side effects are headache, constipation, dizziness, and fatigue.
Yes Ondansetron may be used with or without food.
Use of Ondansetron in pregnant women should be as a result of the possible benefit versus the risk of the drug. Use under the guidance of the doctor.
In case of missing a dose, do it as soon as possible without considering it to be almost time to take your next dose. Do not take two doses at once.
Ondansetron normally takes between 30 to an hour to take effect to prevent nausea and vomiting.
The generic is usually taken on a short-term basis particularly nausea caused by chemotherapy. A healthcare provider should observe long-term usage.
Yes, Ondansetron may have an interaction with some certain antidepressants, anti-seizure drugs, and heart-related drugs.
In case you are affected by any serious side effects such as chest pain or irregular heartbeats, consult a physician at once.
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