| Brand Name | Xeljanz |
| Generic Name | Tofacitinib |
| Drug Class | Janus Kinase (JAK) Inhibitor |
| Availability | Prescription |
| Manufacturer | Pfizer |
| Indications | Ulcerative Colitis, Crohn's Disease |
| Type | Tablet |
| Doses | Oral: 5 mg twice daily (induction), 5 mg once daily (maintenance) |
| Route | Oral |
| Side Effects | Infections, high cholesterol, diarrhea, upper respiratory symptoms |
| Interactions | JAK inhibitor; avoid live vaccines; monitor for infection |
| Overdose | Overdose may cause severe digestive symptoms and electrolyte imbalances. |
| Missed Dose | If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. |
| Contraindications | Active infections, liver disease, drug interactions. |
| Alternatives | Filgotinib, Upadacitinib |
| Co-Pay Assistance Program | Available Rx |
| Patient Assistance Program | Not available |
Dr. Bharat Pothuri is a Board-Certified Gastroenterologist and Hepatologist. With extensive experience in digestive health, he specializes in advanced endoscopic procedures, chronic GI disorder management, and preventive care. Dr. Pothuri is dedicated to providing expert, patient-focused insights to help improve gut health and overall well-being.
Hydrocodone is an opioid pain reliever used in the treatment of moderate to severe painful feelings, and coughing.
The Hydrocodone mechanism of action is that the drug binds to the opioid receptors present in the brain and dental pulp which reduce the perception of pain besides inhibiting coughing.
The side effects are usually constipation, dizziness, drowsiness, nausea, and dry mouth.
Admittedly, Hydrocodone can be given into the body with or without food. The stomach upset may be prevented with the associated eating.
The use of hydrocodone during pregnancy is only needed when there is necessity. Only use it during pregnancy and under the supervision of your doctor.
Not to take your dose on time you should take it as soon as you remember it though not too close to your other dosage. Do not take two doses at once.
The mean time of reaction in hydrocodone is either 30 to 60 minutes, when the drug begins to effect, and in 1-2 hours, the drug reaches its peak.
Hydrocodone is a short term treatment but in case of long term there is need to observe closely so as not to depend on it thus leading to tolerance and other similar problems.
Yes, Hydrocodone can possess interaction also with other drugs particularly the central nervous system depressants like benzodiazepine and alcohol.
Seek medical attention urgently in case you have serious side effects such as experiencing difficulty in breathing, confusion or fainting.
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