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Abnormal Results of Liver Function Studies
Abnormal liver function studies typically indicate that your liver may be inflamed, stressed, or damaged. These results often include elevated liver enzymes, bilirubin, or changes in protein levels. While the cause may be mild and temporary, such as medication effects or diet, they can also point to underlying liver conditions that need further evaluation.
Dr. Scott Liu, MD, is a board-certified gastroenterologist with over six years of experience and a background in military medicine. He earned his medical degree from the University of Maryland, Baltimore, completed his Internal Medicine residency at Naval Medical Center Portsmouth, and finished his Gastroenterology fellowship through the National Capital Consortium. Dr. Liu provides comprehensive care for a broad range of digestive conditions, including abdominal pain, acid reflux, liver disease, chronic diarrhea, and colon cancer screening. He is a member of the American College of Gastroenterology and is known for his disciplined, patient-focused approach and clear communication.
What Is Abnormal Weight Loss?
Abnormal weight loss is defined as an unintentional loss of more than 5% of your body weight over six to twelve months. In medical coding, it's classified under ICD-10 code R63.4. If you haven't changed your diet or exercise routine but are still dropping pounds, it's important to seek a medical evaluation.
Local risk factors in Houston: smoking, poor diabetes control, prolonged stress
Signs and Symptoms
Unintentional weight loss of 5% or more over 6-12 months
Persistent fatigue or generalized weakness
Reduced appetite or early satiety
Abdominal discomfort, bloating, or cramps
Fevers, night sweats, or other systemic signs
How Dr. Scott Diagnoses Abnormal LFTs?
Dr. Scott uses a step-by-step approach:
Medical History & Physical Exam
He reviews your medical and surgical background, alcohol and medication use, family history of liver disease, plus the characteristics of your epigastric pain (onset, location, severity, triggers).
Blood Tests
Comprehensive panels include:
Liver enzymes (AST, ALT, ALP, GGT) and bilirubin to assess hepatocellular injury or cholestasis
Amylase and lipase to rule out pancreatitis as a cause of upper abdominal pain
Complete blood count, coagulation studies, viral hepatitis serologies, iron studies and autoimmune markers if indicated
Imaging Studies
Abdominal ultrasound to evaluate liver texture, fatty infiltration, gallstones and bile duct dilation
FibroScan (transient elastography) or MR elastography to measure liver stiffness and quantify fibrosis
CT or MRI abdomen when deeper evaluation of masses, pancreatic disease or complex anatomy is required
Endoscopy & Advanced Testing
If epigastric pain persists or ulcers are suspected, an upper endoscopy (EGD) will inspect the esophagus, stomach and duodenum. For biliary obstruction, MRCP or ERCP may be performed. In rare cases, a liver biopsy is obtained to confirm the diagnosis and stage inflammation or fibrosis.
Treatment
Our Team offers a full range of treatment options for abnormal weight loss.
1. Diet and Lifestyle Support
Nutrition sessions with a licensed dietitian
Custom meal plans to help you regain weight
Practical tips to manage stress and improve sleep
2. Medications
Vitamin and mineral supplements to correct deficiencies
Targeted therapies for underlying conditions (thyroid disorders, inflammation, gut health)
3. Minimally Invasive Procedures
Endoscopy to evaluate for strictures or blockages
Dilation or stent placement to open narrowed areas
Advanced motility testing to assess digestive function
Dr. Nghia Nguyen, DO, is a board-certified gastroenterologist providing advanced digestive care in the Greater Houston area. He earned his medical degree from the Texas College of Osteopathic Medicine and completed both his Internal Medicine residency and Gastroenterology fellowship at the University of Texas at Rio Grande Valley. Dr. Nguyen specializes in treating conditions such as acid reflux, irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and liver disorders.
Frequently Asked Questions
What is the ICD-10 code for abnormal weight loss?
It's R63.4.
How do I know if my weight loss is abnormal?
If you lose 5% or more of your body weight in 6 to 12 months without trying, it's considered abnormal and warrants evaluation.
Can anxiety cause weight loss?
Yes. Stress and anxiety can suppress appetite and increase metabolic rate, leading to unintentional weight loss.
Will I need an endoscopy?
Possibly. Dr. Scott recommends endoscopy when blood tests and imaging don't fully explain your symptoms.
How long does the diagnosis process take?
Most patients receive a clear diagnosis and treatment plan within 2 to 3 visits.
Do you accept insurance?
Yes. We accept most major plans and will assist you in verifying your benefits.
