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Wilson's Disease

With Dr. Rishi Chadha at GastroDoxs in Houston, Wilson's disease treatment focuses on early diagnosis and personalized care. Comprehensive testing, dietary guidance, medications, and procedures ensure patients receive tailored support to control copper levels and protect liver and brain health.

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Rishi Chadha

About the Expert

Dr. Rishi Chadha, MD is a board‑certified gastroenterologist who specializes in preventive gastroenterology, colorectal cancer screening, and minimally invasive endoscopic procedures. He completed his fellowship at Sunrise Health GME in Las Vegas and previously trained in internal medicine at St. Vincent’s Medical Center in Connecticut.

Common Causes and Risk Factors

  • Inherited genes: You need one faulty gene from each parent
  • Family history: If a close relative has it, your risk is higher
  • Age: Symptoms often start between ages 5 and 35

Signs and Symptoms

  • Feeling tired or weak
  • Belly pain or swelling
  • Yellow skin or eyes (jaundice)
  • Shaky hands or stiff muscles
  • Mood changes like sadness or anger

How Dr. Rishi Chadha Diagnoses Wilson's Disease

1. Comprehensive Health & Family History

Dr. Chadha begins by discussing your personal and family health history, looking for inherited risk factors and early signs of copper overload.

2. Blood Tests for Copper & Liver Function

He orders laboratory panels to measure serum ceruloplasmin, total serum copper, liver enzymes, and other markers that indicate how well your liver is working and whether copper is accumulating.

3. 24-Hour Urine Copper Collection

You'll provide a urine sample collected over 24 hours so Dr. Chadha can quantify how much copper your body is excreting-an important indicator of Wilson's disease.

4. Imaging Studies (Ultrasound or MRI)

  • Abdominal ultrasound to assess liver size, texture, and signs of fatty change or cirrhosis.
  • MRI of the liver (and sometimes brain) to detect early copper deposits and rule out other abnormalities.

5. Liver Biopsy (When Necessary)

In rare or inconclusive cases, Dr. Chadha may recommend a liver biopsy to directly measure hepatic copper content and confirm the diagnosis.

Dr. Rishi Chadha
Treatment

Our Houston team offers a full range of treatment options for Wilson's disease.

1. Lifestyle and Diet Changes

  • Eat low-copper foods: avoid liver, shellfish, nuts, chocolate, and mushrooms
  • Take zinc supplements to block copper absorption
  • Maintain regular checkups every 3-6 months to monitor liver and nerve health

2. Medications

  • Chelating agents (penicillamine or trientine) to bind and remove excess copper
  • Zinc acetate to prevent further copper uptake
  • Individualized dosing and adjustments based on blood and urine copper levels

3. Procedures and Referrals

  • Endoscopy for evaluation and management of gastrointestinal bleeding
  • Liver transplant evaluation if advanced liver failure develops
  • Referral to leading Houston transplant centers when indicated
Rishi Chadha

About the Author

Dr. Rishi Chadha, MD is a board‑certified gastroenterologist who specializes in preventive gastroenterology, colorectal cancer screening, and minimally invasive endoscopic procedures. He completed his fellowship at Sunrise Health GME in Las Vegas and previously trained in internal medicine at St. Vincent’s Medical Center in Connecticut.

Frequently Asked Questions

What is Wilson's disease?

It's a condition where copper builds up in your body and harms your organs.

How is Wilson's disease diagnosed?

Blood tests, a 24-hour urine test, and sometimes liver scans or biopsy.

What are the early signs?

Tiredness, belly pain, tremors, or mood swings.

What should I avoid in my diet?

Liver, shellfish, nuts, chocolate, and mushrooms.

Can it be cured?

No cure yet, but treatment keeps copper levels under control.

How often will I need checkups?

Usually every 3 to 6 months.

Are there side effects from the medicine?

Yes, like nausea or rash-but Dr. Chadha watches for problems.

Can kids get this disease?

Yes, symptoms may begin in childhood or teen years.

Can my family be tested?

Yes, genetic testing can find others at risk.

What if I need a liver transplant?

We'll connect you to Houston's top transplant centers.

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